In this way, the bioprinting of functional autologous solid organs (e.g., kidney or heart) remains an aspirational goal. However, the formation of more simple tissues such as adipose tissue for breast reconstruction, represents a lower-hanging fruit in translational bioprinting research. The ...
Crown-like structures of the breast (CLS-B), defined by the clustering of macrophages (identified using CD68 immunohistochemical staining) to surround a dying adipocyte, are a sign of adipose-tissue inflammation. In human cohorts, CLS-B positively correlates with older age, obesity, dyslipidemia an...
3.Breast augmentation by transplantation of adipose tissue - derived stem cells was featured in The Wall Street Journal. 隆乳移植脂肪组织源性干细胞是精选华尔街日报. 4.Adipose tissue triacylglycerols are the quantitatively most important source of stored energy in animals. ...
Introduction/aims Obesity, an excess accumulation of adipose tissue occurring in mammalians when caloric intake exceeds energy expenditure, is associated with an increased incidence, morbidity and mortality from several types of neoplastic diseases including postmenopausal breast cancer. Methods and results ...
Adipose tissueconstitutes the fat of meat. 脂肪组织构成了肥肉. 互联网 Adipose tissueaggregate of fat cells. 脂肪组织有大量的脂肪细胞聚集而成. 互联网 Breast augmentation by transplantation ofadipose tissue- derived stem cells was featured in The Wall Street Journal. ...
breast cancer growth and progression. A numberof advances have been made in recent years revealing new insights into this link. Earlyevents in breast cancer development involve the neoplastic transformation of breastepithelial cells to cancer cells. In obesity, breast adipose tissue undergoes signif i...
Recent studies have shown that cells from adipose tissue are capable of trafficking to tumors, thus enabling paracrine action of adipokines from within the tumor microenvironment. Increased tumor vascularization, immune system suppression and direct effects on malignant cell survival and proliferation have ...
Fig. 1: Schematic overview of the study design. aSample population information;bSample tissue information;cIllustration of the data types used in the study. Histological analysis was used to measure adipocyte size; gene expression and lipid profiles were quantified by transcriptomic and lipidomic anal...
includes increased inflammation,angiogenesisand alterations in circulating levels of adipocyte-derived factors such as leptin,adiponectinandtumor necrosis factor(TNF). Higher circulating levels of leptin and TNF, found in obese women, enhance breast tumor growth as supported byin vitroandin vivostudies [...
Accumulation of adipose tissue macrophages (ATMs) is observed in obesity and may participate in the development of insulin resistance and obesity-related complications. The aim of our study was to investigate the effect of long-term dietary intervention on ATM content in human adipose tissue. Design...