In this study, we suggest that NHDFs can be converted into adipocyte-like cells by an adipogenic cocktail and can serve as a useful tool for studying human adipocytes and their metabolism.Sunkyu ChoiRajaa S. D. DalloulPraveen Babu Vemulapalli...
It proposes anapproach that could prove very useful to better characterize the WAT brown adipocyte-like cells.L LehrK CanolaB LégerJ-P GiacobinoInternational Journal of ObesityLehr, L., Canola, K., Leger, B. and Giacobino, J.P. (2009) Differentiation and Characterization in Primary Culture...
Biphasic Alteration of Glucose Transport in 3T3-L1 Cells During Differentiation to the Adipocyte-Like PhenotypeBiphasic Alteration of Glucose Transport in 3T3-L1 Cells During Differentiation to the Adipocyte-Like PhenotypeZiehmD.SchuermannA.WeilandM...
Much is known about the contribution of various stromal vascular cells to the remodeling process, but less is known of the changes that occur within the adipocyte as it becomes progressively dysfunctional. Here, we performed a transcriptome analysis of isolated vWAT adipocytes to assess global ...
Neural stem cells (NSCs) persist throughout life in two forebrain areas: the subventricular zone (SVZ) and the hippocampus. Why forebrain NSCs self-renew m... CA Fasano,TN Phoenix,E Kokovay,... 被引量: 0发表: 0年 Bmi-1 cooperates with Foxg1 to maintain neural stem cell self-renewal...
dlk gene mRNA encoding for secreted variants decreased much faster than total dlk gene mRNA during differentiation of 3T3-L1 cells. In fact, total dlk or membrane-associated dlk protein expression increased during the first hours of differentiation. Cells sorted for lowest levels of dlk protein ...
Mesenchymal Stem Cells (MSCs)Ras-related C3 Botulinum Toxin Substrate 1 (Rac1)RhoGDIβSmooth Muscle-like CellsThe integration of signals involved in deciding the fate of mesenchymal stem is largely unknown. We used proteomics profiling to identify β, an inhibitor of the Rho family, as a ...
We show that adipose tissue CD206+ cells are primarily M2-like macrophages, and ablation of CD206+ M2-like macrophages improves systemic insulin sensitivity, which was associated with an increased number of smaller adipocytes. Mice genetically engineered to have reduced numbers of CD206+ M2-like ...
We show that adipose tissue CD206cells are primarily M2-like macrophages, and ablation of CD206M2-like macrophages improves systemic insulin sensitivity, which was associated with an increased number of smaller adipocytes. Mice genetically engineered to have reduced numbers of CD206M2-like macrophages...
cells in adipose tissues are macrophages, but not cells of other lineages. Consistently, F4/80 messengerRNA (mRNA) expression levels in F4/80 + CD206 + populations compared with those in total SVF populations (Fig. 1b, black/blue ratios) were equivalent to the relative levels of the well-...