G protein-coupled receptors (GPCR) are well-characterized regulators of a plethora of physiological functions among them the modulation of adipogenesis and adipocyte function. The class of Adhesion GPCR (aGPCR) and their role in adipose tissue, however, is poorly studied. With respect to the ...
G protein-coupled receptors (GPCR) are well-characterized regulators of a plethora of physiological functions among them the modulation of adipogenesis and adipocyte function. The class of Adhesion GPCR (aGPCR) and their role in adipose tissue, however, is poorly studied. With respect to the deman...
In contrast, ONX0914 addition during the first two days blocked the upregulation of all three mole- cules, and their levels remained low during the next six days (Fig. 3c). These data demonstrate that Psmb8 activity directly regulates the differentiation of preadipocytes to mature adipocytes...
However, probably as a consequence of their hyperglycemia, these mice have reduced nerve conduction velocity, thus mimicking the phenotype observed under diabetic condition. Together, our data indicate that while adipocytes, as regulators of lipid and glucose homeostasis, play a role in nerve function...
Describe how carbohydrates, proteins, and fats are used to meet the energy needs of the body. What part of a cell makes lipids? How are ciliated epithelial cells adapted to their function? Does fat help with cell signaling? How are catabolism and anabolism linked with the cardiovascular system...
Adipose Tissue | Definition, Function & Location from Chapter 29 / Lesson 13 194K Learn what adipose tissue is and how it is referred to as fat. Discover where the adipose tissue is found, about adipose cells, and the function of the fatty tissue. Related...
17 UCP2 and UCP3 share amino acid identity with UCP1 (59 and 57%, respectively), and their function in mitochondrial uncoupling is still under investigation.14,15,18 Although some studies suggested that UCP2 and UCP3 were proton channels like UCP1, others regarded them as ion channels that...
The findings of this research demonstrate that 7-MEGA™ exhibits promise as a therapeutic approach for obesity-related conditions by influencing adipocyte function. This includes inhibiting the formation of fat cells and reducing lipid accumulation. Therefore, results suggest that 7-MEGA has the ...
In the adipocyte, the vast majority of fatty acids are derived from triacylglycerols with minor contributions from species such as phospholipids. Palmitate, stearate and their unsaturated derivatives were the most common—accounting for >90% of the total lipid. To standardize between experiments, we ...
In addition to their function in energy metabolism and regulation of energy homeostasis, adipocytes also secrete hormone and various cytokines (also known as adipokines)9, which participate in cancer progression. For instance, IGF-1, leptin and interleukin-6 (IL-6) secreted from adipocytes promote ...