et al. The epidermal growth factor-like domains of the human EMR2 receptor mediate cell attachment through chondroitin sulfate glycosaminoglycans. Blood 102, 2916–2924 (2003). Article CAS PubMed Google Scholar Luo, R. et al. G protein-coupled receptor 56 and collagen III, a receptor-ligand...
TSPO deficiency promotes the progression of malignant peripheral sheath tumors by regulating the G2/M phase of the cell cycle via CDK1 Xingnan Zhang , Chenhao Hu & Song Liu Article 05 October 2024 | Open Access Desmoplakin CSM models unravel mechanisms regulating the binding to intermediate...
Several markers, including stage-specific embryonic antigen-1 (SSEA-1), sex-determining region Y-box 9 (SOX9), neural-cadherin (N-cadherin), leucine-rich-repeat-containing G-protein-coupled receptor 5 (LGR5), CD44, axis inhibition protein 2 (Axin2), and aldehyde dehydrogenase 1A1 (ALDH1...
96-well bacterial plates were precoated (2 h at 22 °C) with 100 µl of monoclonal antibodies (106.1), anti-P-Tyr (α-PY), anti-insulin receptor (extracellular) α subunit (α-IR), goat anti-mouse antibodies, or anti-erb2 monoclonal antibodies, each added at 40 µg/ml unless ...
lateral interactions could act as a regulating factor for downstream signaling pathways, and that lateral interactions of adhesion molecules could be important in setting the proper intermembrane distance at adhesion sites, hence providing a scaffold for further receptor-ligand interactions between membranes...
G-protein coupled receptors, transmembrane receptors and kinases (Table S2), had more than fivefold log change in expression between the VAP-1+and VAP-1−HSC populations. Of all differentially expressed genes (Fold change > 2,p-value < 0.05), 516 were up-regulated in the VAP-1...
The enormous sizes of adhesion G protein-coupled receptors (aGPCRs) go along with complex genomic exon-intron architectures giving rise to multiple mRNA variants. There is a need for a comprehensive catalog of aGPCR variants for proper evaluation of the
et al. The oligodendrocyte-specific G-protein coupled receptor GPR17 is a cell-intrinsic timer of myelination. Nat. Neurosci. 12, 1398–1406 (2009). 48. Xu, L., Begum, S., Hearn, J. D. & Hynes, R. O. GPR56, an atypical G protein- coupled receptor, binds tissue transglutaminase,...
Membrane recruitment of the polarity protein Scribble by the cell adhesion receptor TMIGD1 Eva-Maria Thüring, Christian Hartmann, Janesha C. Maddumage, Airah Javorsky, Birgitta E. Michels, Volker Gerke, Lawrence Banks, Patrick O. Humbert, Marc Kvansakul & Klaus Ebnet Communicatio...
The adhesion G-protein-coupled receptor (GPCR) latrophilin 3 (ADGRL3) has been associated with increased risk of attention deficit hyperactivity disorder (ADHD) and substance use in human genetic studies. Knockdown in multiple species leads to hyperlocom