the physiological benefits of such selectivity, and specifically speak to the possibility of unlocking the widespread clinical potential of A1R agonists. Results The novel A1R agonist BnOCPA exquisitely discriminates between native pre- and postsynaptic A1Rs in the intact mammalian CNS BnOCPA (Fig.1a)...
The prodrug approach has emerged as a promising solution to combat bacterial resistance and enhance treatment efficacy against bacterial infections. Here, we report an adenosine triphosphate (ATP)-activated prodrug system for on-demand treatment of bacterial infection. The prodrug system benefits from the...
We'll explore more of the research into caffeine's benefits in a bit, but for now it's important to note that most Americans consume the bulk of their caffeine -- intentionally or not -- as a form of self-medication. Grabbing a cup of coffee when they need a pick-me-up, for examp...