ADA deficiency may be treated with gene therapy or bone marrow transplantation or by enzyme replacement with polyethylene glycol adenosine deaminase (Peg-ADA). In case of the defect, deoxyadenosine (dAdo) or deoxyadenosine triphosphate reaches toxic levels. Into T lymphocytes isolated from the patients...
必应词典为您提供adenosine-deaminase-deficiency的释义,网络释义: 腺苷脱氨酶缺乏症;腺嘌呤去胺酶缺乏症;腺苷酸脱氨酶缺乏症;
Adenosine deaminase deficiency, orADA deficiency, is an inherited immunodeficiency syndrome accounting for about 25% of all cases of severe combined immunodeficiency (SCID). This disease is due to a lack of theenzymeadenosine deaminase coded for by a gene on chromosome 20. There is an accumulation...
Medical Editor:Melissa Conrad Stöppler, MD homemedical dictionary Adenosine deaminase (ADA) deficiency:A genetic (inherited) condition that results in a immune deficiency disorder called severe combined immunodeficiency disease.Adenosine deaminaseis an enzyme that plays a key role in salvagingpurinemolecu...
分享到: 腺苷脱氨酶缺乏症 分类: 医学|查看相关文献(pubmed)|免费全文文献 详细解释: 以下为句子列表: 分享到:
分享到: 腺苷脱氨酶缺乏症 分类: 遗传学|查看相关文献(pubmed)|免费全文文献 详细解释: 以下为句子列表: 分享到:
ADA deficiency may be treated with gene therapy or bone marrow transplantation or by enzyme replacement with polyethylene glycol adenosine deaminase (Peg-ADA). In case of the defect, deoxyadenosine (dAdo) or deoxyadenosine triphosphate reaches toxic levels. Into T lymphocytes isolated from the patients...
Adenosine deaminase (ADA) is a protein produced by cells throughout the body and is associated with the activation of lymphocytes, a type of white blood cell that plays a role in the immune response to infections. The adenosine deaminase test may be used
14: 885-889 (1980) adenosine deaminase deficiency infant metabolism severe combined immunodeficiency Adenosine Deaminase Deficiency Without Immunodeficiency: Clinical and Metabolic Studies WILLIAM BORKOWSKY, M.D., ANNE A. GERSHON, M.D., LOUIS SHENKMAN, M.D., AND ROCHELLE HIRSCHHORN, M.D.'46' ...
and present at 1–8 years of age; several adults have been diagnosed at 15–39 years. Some healthy children and adults with very low erythrocyte ADA activity but with significant ADA activity in nucleated cells have been identified by screening and have been designated “partial ADA deficiency....