Medical Editor:Melissa Conrad Stöppler, MD homemedical dictionary Adenosine deaminase (ADA) deficiency:A genetic (inherited) condition that results in a immune deficiency disorder called severe combined immunodeficiency disease.Adenosine deaminaseis an enzyme that plays a key role in salvagingpurinemolecu...
ADA deficiency may be treated with gene therapy or bone marrow transplantation or by enzyme replacement with polyethylene glycol adenosine deaminase (Peg-ADA). In case of the defect, deoxyadenosine (dAdo) or deoxyadenosine triphosphate reaches toxic levels. Into T lymphocytes isolated from the patients...
adenosine deaminase deficiency 读音:美英 adenosine deaminase deficiency基本解释 腺苷脱氨酶缺乏症 分词解释 adenosine腺苷 deaminase脱氨(基)酶 deficiency缺乏,不足
Speculation The finding that the patient's lymphocytes can deaminate aden- osine to some extent may explain why the rate of adenosine incorporation into purine ribonucleotides of his lymphocytes is not increased and immune function is not impaired. Deficiency of erythrocyte adenosine deaminase results ...
Deficiency of adenosine deaminase (ADA) results in severe combined immunodeficiency. Clinical cure has been observed in several ADA-severe combined immunodeficiency patients after bone marrow transplantation in which only donor T cells were engrafted, suggesting that T-cell correction alone is sufficient ...
ABSTRACT: Deficiency of adenosine deaminase (ADA) results in severe combined immunodeficiency. Clinical cure has been observed in several ADA-severe combined immunodeficiency patients after bone marrow transplantation in which only donor T cells were engrafted, suggesting that T-cell correction alone is ...
Adenosine deaminase (ADA) deficiency is best known as a form of severe combined immunodeficiency (SCID) that results from mutations in the gene encoding AD... KV Whitmore,HB Gaspar - 《Frontiers in Immunology》 被引量: 18发表: 2016年 Adenosine deaminase deficiency: a review Adenosine deaminase ...
Related to adenosine deaminase: Adenosine deaminase deficiencyThesaurusAntonymsRelated WordsSynonymsLegend: Switch to new thesaurus Noun 1. adenosine deaminase - an enzyme found in mammals that can catalyze the deamination of adenosine into inosine and ammonia; "ADA deficiency can lead to one form of...
Adenosine deaminase (ADA) deficiency causes lymphopenia and immunodeficiency due to toxic effects of its substrates. Most patients are infants with severe combined immunodeficiency disease (SCID), but others are diagnosed later in childhood (delayed onset) or as adults (late onset); healthy individuals...
必应词典为您提供adenosine-deaminase-deficiency的释义,网络释义: 腺苷脱氨酶缺乏症;腺嘌呤去胺酶缺乏症;腺苷酸脱氨酶缺乏症;