ADAM17 GENE EXPRESSION IN LASER-CAPTURE MICRODISSECTED BREAST CANCERSNarita, DianaSeclaman, EdwardIlina, RazvanCireap, NataliaPribac, George CiprianArdelean, AurelNicola, TiberiuAnghel, AndreiStudia Universitatis Vasile Goldis Seria Stiintele Vietii (Life Sciences Series)...
Characteristics Structure The 50kb ADAM17 gene, which is located at chromosome 2p25, consists of 19 exons and encodes an 824 amino acid protein. ADAM17 is synthesized as an inactive precursor protein consisting of five domains: the pro-, metalloprotease, cysteine-rich, transmembrane, and ...
The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway. [provided by RefSeq, Jul 2008] [中文简述(自动翻译):] 该基因编码的ADAM(解...
Gene ID (NCBI) 6868 Alternative Names ADAM18;CD156B;CSVP;NISBD;NISBD1;TACE Application Notes: The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user. WB 1:500 - 1:2000 ...
基因名称 Adam17 Gene ID 11491 品系名称 遗传背景 C57BL/6J 修饰方式 KO 应用领域 表型 大多数该基因的靶向突变纯合的小鼠围产期死亡,伴有发育不良的触须和睁开的眼睑。幸存者表现出不同程度的眼睛退化,毛发被扰乱,卷曲的触须和不规则的色素沉积模式。胎儿的组织学分析显示在多个器官的成熟上皮细胞和组织有缺陷。
Entrez Gene:84578只老鼠Omim:605166个人SwissProt:O1579人SwissProt:O88 895小鼠SwissProt:Q6P6W3大鼠 重要注意事项:所提供的产品仅用于研究用途,不用于人体、治疗或诊断应用。 肿瘤坏死因子α转换酶ADAM17产产品图片: 组织/细胞:大鼠脑组织;4%多聚甲醛固定和石蜡包埋;抗原提取:柠檬酸缓冲液(0.01M,pH 6),15min...
10. Zhongshan Cheng, Jie Zhou, Kelvin Kai-Wang To et al. Identification of TMPRSS2 as a susceptibility gene for severe 2009 pandemic A(H1N1) infuenza and A(H7N9) influenza. Journal of Investigative Dermatology. 2015.11. Manon Laporte and Lieve Naesens. Airway proteases: an emerging drug ...
Gene Symbol ADAM17 Gene ID (NCBI) 6868 Conjugate Unconjugated Form Liquid Purification Method Protein A purification UNIPROT ID P78536 Storage Buffer PBS Only Storage Conditions Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°CProteintech...
Gene Info — ADAM17 Interactomes Pathways Diseases Related Products H00006868-M01J ADAM17 monoclonal antibody (M01J), clone 1F6 MAB19529 ADAM17 monoclonal antibody, clone AOIO-1 PAB29576 ADAM17 polyclonal antibody H00006868-M01A ADAM17 monoclonal antibody (M01A), clone 1F6 ...
7. Ariane Paoloni-Giacobino, Haiming Chen, Manuel C. Peitsch et al. Cloning of the TMPRSS2 gene, which encodes a novel serine protease with transmembrane, LDLRA, and SRCR Domains and maps to 21q22.3. Genomics. 1997. 8. Ilona Glowacka, Stephanie Bertram, Marcel A. Muller et al. Evide...