acyltransferasechildhoodfibrosisobesitysteatosisBackground: The rs641738 polymorphism in the membrane-bound Oacyltransferase domain containing protein 7 (MBOAT7) gene has been associated with increased risk of nonalcoholic fatty liver disease (NAFLD).Di Sessa, AnnaUmano, Giuseppina RosariaCirillo, Grazia...
别名: FKSG89; ghrelin o transferas; Ghrelin O-acyltransferase; GOAT; MBOA4_HUMAN; Mboat4; Membrane-bound O-acyltransferase domain-containing protein 4; O-acyltransferase (membrane bound) domain containing 4; O-acyltransferase domain-containing protein 4; OACT4. 宿主...
a basic leucine zipper-domain containing TF CBL cocoa butter-like lipid CCT CTP:phosphocholine cytidylyltransferase Core HCV capsid protein CPM 7-diethylaminl-3-(4’-maleimidyl-phenyl)-4-methylcoumarin CPT CDP-choline:1,2-diacylglycerol cholinephosphotransferase ...
Protein S-palmitoylation is a reversible post-translational modification that is mediated by palmitoyl acyltransferases, which are a group of Zn2+-finger DHHC domain-containing proteins (ZDHHC)[68]. Zdhhc13 knockout reduced Drp1 S-palmitoylation in the cortex and was accompanied by altered ...
Intracellular localization and tissue-specific distribution of human and yeast DHHC cysteine-rich domain-containing proteins. Biochim. Biophys. Acta 1761, 474–483 (2006). Article CAS PubMed Google Scholar Kokkola, T. et al. Somatostatin receptor 5 is palmitoylated by the interacting ZDHHC5 ...
TMEM68 has two putative transmembrane domains and is localized to the endoplasmic reticulum via the first transmembrane domain [24]. Overexpression of TMEM68 elevated TAG levels and enhanced LD accumulation in HEK293 and MCF-7 cells, depending on the conserved catalytic motif I [25]. An in ...
We confirmed that three of them, GPM6A, and the Sprouty domain-containing proteins SPRED1 and SPRED3, are indeed palmitoylated by HIP14; the first enzyme known to palmitoylate these proteins. These novel substrates functions might be affected by reduced palmitoylation in HD. We also show that...
PNPLA3 (Patatin-like Phospholipase Domain-containing Protein 3, Acylglycerol O-acyltransferase, Adiponutrin, Calcium-independent Phospholipase A2-epsilon, iPLA2-epsilon, ADPN, C22orf20, dJ796I17.1, FLJ22012) 供应商 MyBioSource 产品货号
Each domain required 15–30 amino acids for basal recognition and 50–80 amino acids for wild-type acylation. The two domains (FAI and FAII) competed with each other in cis and in trans for HlyC. The affinity of FAI for HlyC is approximately four times greater than that of FAII resulting...
Here, we show that ART binds and inhibits the zinc finger DHHC domain-containing protein 6 (ZDHHC6) to reduce NRas palmitoylation in cancer cells. The decrease in palmitoylation further disrupts NRas Golgi localization and its subcellular redistribution, thereby attenuating the downstream signaling ...