acyl halidealdehydeenantioenriched β-lactonesoxetanoneswaste disposalS )-Valinol Triethylamine Trifluoromethanesulfonic anhydride ( S )- N -Trifluoromethylsulfonyl-2-isopropylaziridine Benzylamine (2 S ,6 S )-4-Benzyl-1,7-bis(trifluoromethylsulfonyl)-2,6-disopropyll-1,4,7-triazaheptane Disio...
Scott G. Nelson, et al., " Catalytic Asymmetric Acyl Halide-Aldehyde Cyclocondensation Reactions of Substituted Ketenes ", J. AM. Chem. Soc., 2004, pp. 14-15, vol. 126, American Chemical Society, XP-00230604.Catalytic asymmetric acyl halide-aldehyde cycloconde-nsation reactions of ...
Catalytic Asymmetric Propionate Aldol Reactions via Acyl Halide−Aldehyde Cyclocondensations - Nelson, Wan () Citation Context ...2 C (5) +0.07 C (6) −0.22 C (6) −0.24 C (6) −0.23 C (7) −0.41 C (7) −0.40 C (7) −0.41 H (8) +0.26 H (8) +0.26 H (8) ...
Nelson, Scott G., et al; Catalyzed acyl halide-aldehyde cyclocondensations. New insights into the design of catalytic cross aldol reactions; Tetrahedron Letters;40;(1999); pp. 6535-6539.Nelson S G,Wan Z H,Peelen T J. Catalyzed acyl halide-aldehyde cyclocondensations. New insights into the...
The reaction tolerates thiophene-, halide- (F, Br), ester-, ether-, and alkyl-substituted aryl alcohols in moderate to good yield (20OL4979). Similar homotryptamine substrates were utilized in a hypoiodite-catalyzed tandem dearomative peroxycyclization for the synthesis of peroxy- and epoxy...
The low reactivity of acyl fluoride with water leads to a great storage stability of acyl-fluoride-activated substrates, even under humid conditions. On the contrary, other acyl halides readily react with trace amounts of water in the air, which hinders the long-term storage of halide-acyl-...
In a method for preparing a ketone of formula IVa, wherein Z is --CH2 -- and p is 1, a nitrile of formula VIII is treated with a suitable base, such as NaH, then reacted with a halide of formula IX to form a nitrile of formula X. Alternatively, the nitrile VIII is treated ...
The N9-alkylated derivative of compound 4a was prepared by the action of sodium hydride (NaH) in anhydrous N,N-dimethylformamide (DMF) followed by the addition of alkyl halide to afford compounds 4h–l, and following this, the intermediates 6h–l and 7h–l were prepared according to the sam...
A chilled N-acyl selone is reacted with a Lewis acid such as TiCl 4 and mixed with a tertiary amine such as diisopropylethylamine to generate an enolate solution. Upon further chilling of the enolate solution a desired aldehyde is added and after an acceptable reaction period a quencher is...
As for this invention, aromatic aldehyde or the aromatic aldehyde blend xylene being the method of converting to the reaction product which in the reaction medium which is not included is aromatic acyl halide or the aromatic acyl halide blend, halogen and contact obtaining aromatic aldehyde or the...