Mousemodelsofacutepromyelocyticleukemiahavebeen generatedthroughtransgenic,knock-in,retroviral,andxenograftstrategies. 小鼠模型的急性早幼粒细胞白血病已通过转基因,基因敲除中,逆转录病毒,以及异种战略。 www.syyxw.com 2. Theauthorsrecommendedthat thetreatmentbegiven topatientswithbloodandbone marrowcancer,oracutepro...
Acute promyelocytic leukemia (APL) is characterised by balanced translocation between the longarms of chromoso)ne 15 and 17 resulting in formation of fusion protein PMLlRARa. Due to thisabnormal fusion protein, myeloid cell differentiation is arrested at the promyelocyte level. Thismolecular defect ...
acute promyelocytic leukemia 急性早幼粒细胞性白血病 promyelocytic leukemia 早幼粒细胞性白血病 acute leukemia 急性白血病 acute lymphatic leukemia 急性淋巴细胞性白血病 acute nondifferentiated leukemia 急性未分化性白血病 acute erythroblastic leukemia 急性成红细胞白血病 acute histiocytic leukemia 急性组织细...
treatment of acute promyelocytic leukemia and cryopyrin-associated periodic syndromes respectively. legco.gov.hk 局長提供的補充資料顯示,含有該等物質的藥物分別用於 治療急性早幼粒細胞白血病及cr yopyrin相關周期性綜合症。 legco.gov.hk [...] innovative research that led to the successful development ...
医生分析：急性早幼粒细胞白血病属于急性髓系白血病中的一种，也就是M3,多数病人伴有PML/RARa融合基因阳性表达，治愈率很高，亚砷酸、维甲酸、中药雄黄都是这个病的特效药物。现在病人有肺部感染，化疗后机体免疫功能下降，加重感染，不容易控制。医生建议：先抗感染治疗后再考虑化疗，如果抗生素治疗效果不...
(redirected fromacute promyelocytic leukemia) Thesaurus Medical Acronyms Encyclopedia Wikipedia leu·ke·mi·a (lo͞o-kē′mē-ə) n. Any of various acute or chronic neoplastic diseases of the bone marrow in which unrestrained proliferation of white blood cells occurs, usually accompanied by anemi...
Acute promyelocytic leukemia(APL) is characterized by the t(15;17) chromosomal translocation leading to the formation of the PML-RARalpha oncoprotein. This... D Grimwade,AR Mistry,E Solomon,... - 《Cancer Treat Res》 被引量: 750发表: 2010年 Management of acute promyelocytic leukemia Extramedul...
Use of all trans retinoic acid in the treatment of acute promyelocytic leukaemia. Blood 72, 567–572 (1988). CAS PubMed Google Scholar Chen, G.-Q. et al. In vitro studies on cellular and molecular mechanisms of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia. ...
Historically, acute promyelocytic leukemia (APL) was considered to be one of the most fatal forms of acute leukemia with poor outcomes before the introduction of the vitamin A derivative all-trans retinoic acid (ATRA). With considerable advances in thera