Acute myeloid leukemia (AML) is the most common acute leukemia in adults, with an incidence of over 20 000 cases per year in the United States alone. Large chromosomal translocations as well as mutations in the genes involved in hematopoietic prolifer
Progress in the understanding of the biology and therapy of acute myeloid leukemia (AML) is occurring rapidly. Since 2017, nine agents have been approved for various indications in AML. These included several targeted therapies like venetoclax, FLT3 inhi
apoptosis acute myeloid leukemianatural productsalkaloidsRecent findings have shown great potential of alternative interventions such as immunotherapy and natural products for acute myeloid leukemia (AML). This study aims to review the anti-AML effect of various natural compounds. Natural compounds were ...
The stem cells of acute myeloid leukemia (AML) are the malignancy initiating cells whose survival ultimately drives growth of these lethal diseases. Here we review leukemia stem cell (LSC) biology, particularly as it relates to the very heterogeneous nature of AML and to its high disease...
Pediatric acute myeloid leukemia (AML) is a heterogeneous disease with different morphologic, phenotypic, and genetic features, and variable clinical outcomes.1,2 Over the past few decades, outcomes for pediatric AML have improved substantially, with overall survival reaching 60% to 70% and event-fr...
Related to acute myeloid leukemia:Chronic Myeloid Leukemia ThesaurusAntonymsRelated WordsSynonymsLegend: Switch tonew thesaurus Noun1. acute myeloid leukemia- acute leukemia characterized by proliferation of granular leukocytes; most common in adolescents and young adults ...
Acute myeloid leukemia (AML) is a heterogeneous group of neoplastic disorders with great variability in clinical course and response to therapy, as well as in the genetic and molecular basis of the pathology. Major advances in the understanding of leukemogenesis have been made by the characterization...
Acute myeloid leukemia( AML ) is a clonal and heterogeneous disease characterized by a myriad of genetic defects. 急性髓性白血病 ( acutemyeloid leukemia, AML ) 是一类起源于造血干细胞的、以大量遗传缺陷为特征的异质性恶性血液病. 互联网 Methods: Induction regiment ofacute myeloid leukemia( AML ) co...
View article A concise review on the molecular genetics of acute myeloid leukemia Devipriya Padmakumar, ... Hariharan Sreedharan, in Leukemia Research, 2021 1 Introduction Acute myeloid leukemia (AML) is a disorder of bone marrow that results from the clonal expansion of genetically altered hema...
Article Open access 09 November 2023 Targeting multiple signaling pathways: the new approach to acute myeloid leukemia therapy Article Open access 18 December 2020 References Warrell, R., de Thé, H., Wang, Z. & Degos, L. Acute promyelocytic leukemia. N. Engl. J. Med. 329, 177–189...