Cystic fibrosis (CF) lung disease is characterized by a neutrophilic infiltrate that is excessive relative to the burden of infection. Decreased interleukin-10 in CF airways may impair proper termination of inflammation, leading to persistence of neutrophils after acute infections have been cleared. Thi...
Self-Limited versus Delayed Resolution of Acute Inflammation: Temporal Regulation of Pro-Resolving Mediators and MicroRNA Gabrielle Fredman*, Yongsheng Li*, Jesmond Dalli, Nan Chiang & Charles N. Serhan Center for Experimental Therapeutics and Reperfusion Injury, Harvard institutes of Medicine, ...
S. The gut microbiome regulates psychological-stress-induced inflammation. Immunity 53, 417–428 (2020). CAS PubMed PubMed Central Google Scholar Viswanathan, K. & Dhabhar, F. S. Stress-induced enhancement of leukocyte trafficking into sites of surgery or immune activation. Proc. Natl Acad. ...
(CFTR), which has an important role in transepithelial salt transport.1 The major organ affected in CF is the lung, with remorseless and intense chronic airway infection resulting from disabled clearance of dehydrated airway surface liquid.2 Airway inflammation leading to end stage lung damage is ...
The genus Prevotella in cystic fibrosis airways PrevotellaPulmonary infectionSputumPolymicrobial infectionsAirway disease resulting from chronic bacterial colonization and consequential inflammation is the leading ... Tyler R. Field a,Christopher D. Sibley a,Michael D. Parkins a b c,... - 《Anaerobe》...
In contrast, aerobic and anaerobic bacteria and perhaps chlamydiae often cause inflammation below the basement membrane,33 which can result in fibrosis and permanent tubal damage. Inflammation can also spread to the muscularis and serosal layers. The tubal lumen remains open early in the...
acute inflammation of the pancreas in a child 1 acute pancreatitis may be limited to a single episode, or may recur and/or progress to chronic pancreatitis 1, 2, 3 Also Called pediatric pancreatitis Definitions International Study Group of Pediatric Pancreatitis: In Search for a Cure (INSPPIRE...
Inchronic pancreatitis, the damage to the pancreatic tissue is extensive usually affecting both the exocrine and endocrine parenchyma. Fibrosis of the pancreatic tissue is present due to the prolonged inflammation. The damage associated withchronic pancreatitisis usually irreversible. ...
In bronchitis, the irritation to the bronchi and bronchioles triggers the excessive secretion of mucus (hypersecretion). Coupled with the swelling of the wall due to inflammation, the mucus narrows the airway. While a cough is always present, it is not uncommon for other symptoms to be absent...
Severe inflammation of Calot's triangle can produce fibrosis with alteration of all anatomic landmarks and consequent risk of iatrogenic injury to the common hepatic duct, the common bile duct and the cystic duct [35,36,37]. According to the Tokyo 2018 guidelines, the degree of severity of ...