injury, but their presence continually incites chronic inflammatory and immune responses. Some microbial agents can induce macrophages to undergoapoptosisand subsequentinternalizationby adjacent macrophages. Tissue destruction,granulomatous inflammation, andfibrosisare commonsequelaeof persistent/resistant infectious ...
Grading and staging systems for inflammation and fibrosis in chronic liver diseases. Journal of Hepatology 2007;47:598-607.Zachary D. Goodman.??Grading and staging systems for inflammation and fibrosis in chronic liver diseases[J]Journal of Hepatology . 2007 (4)...
Erica Herzog and colleagues put forward the opinion that fibrocytes, a little-studied population of monocyte-derived cells that have properties of both macrophages and fibroblasts, have unique roles in chronic inflammation that warrant further study. Fib
Inflammation and Regeneration All Volumes & Issues Open Access Chronic inflammation and fibrosis ISSN: 1880-8190 (Online) In this topical collection (2 articles) Review Cardiac regeneration by direct reprogramming in this decade and beyond Hiroyuki Yamakawa, Masaki Ieda Article:20 Download PD...
Over the past decade, there has been a renewed enthusiasm for developing noninvasive serum markers or tests to assess the presence and severity of chronic inflammation and fibrosis in chronic liver disease. Although a single marker or test has lacked the necessary accuracy to predict fibrosis, diff...
Metabolism at the crossroads of inflammation and fibrosis in chronic kidney disease Article17 September 2024 Introduction Chronic kidney disease (CKD) is defined as a decline in renal function [glomerular filtration rate (GFR) <60 mL/min per 1.73 m2] or abnormal markers of kidney injury, ...
inflammation. However, inflammation could be either acute or chronic. Acute inflammation persists for a short duration and is the host defense against infections and allergens, whereas the chronic inflammation persists for a long time and leads to many chronic diseases including cancer, cardiovascular ...
Vascular damage, fibrosis, and chronic inflammation in mechanical back pain problemsOur current hypothesis is that mechanical damage in the spine such as a disc prolapse can lead directly to pain. However, pain arising for this reason is usually of short duration. In many subjects, however, the...
Chronic Inflammation Chronic inflammationarises from unresolved sources offoreign bodies,irritants, infections, or autoimmune disorders. This type of inflammation can be described as unregulated and can last for months or years causing tissue destruction,fibrosis, and necrosis. Some prominent characteristics...
5). In the pathology of NASH, oxidative stress acts as a second hit31, leading to lipid peroxidation, mitochondrial damage, hepatocellular injury, and finally chronic inflammation and fibrosis. Proteome profiles were significantly enriched in features of peroxisomal proliferation, liver steatosis and ...