Activator protein 1-mediated transcriptional regulation strategy sustains long-term expression of a xenogeneic gene product in vivo: an implication for gen... Activator protein 1-mediated transcriptional regulation strategy sustains long-term expression of a xenogeneic gene product in vivo: an implication...
Interleukin (IL)-1β is a major catabolic pro-inflammatory cytokine involved in cartilage destruction-associated processes, such as loss of the differentiated chondrocyte phenotype (dedifferentiation) and inflammation. Here, we investigated the role of c-Jun and activator protein-1 (AP-1) in IL-1...
Here, the diminishing effect of activator protein 1 (AP-1) blocking with a synthetic retinoid (SR11302) on the severity of aGVHD in a murine model was investigated. MHC-mismatched strain combinations were used in vivo: C57BL/6 (H-2kb) donors into lethally irradiated BALB/c (H-2kd) ...
产品名称:c-Fos/activator protein(AP)-1抑制剂 英文名称:T-5224 产品货号:M06974 产品规格:1mL(10mM)|5mg|10mg|50mg|100mg T-5224是一种有效的c-Fos/activator protein(AP)-1抑制剂,同时抑制MMP的活性,对MMP-3和MMP-13的IC50值均为10nM。
The yeast heme activator protein Hap1 binds to DNA and activates transcription of genes encoding functions required for respiration and for controlling oxidative damage, in response to heme. Hap1 contains a DNA-binding domain with a C6 zinc cluster motif, a coiled-coil dimerization element, typical...
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This specificity depends critically on the presence of an activator protein 1 (AP1) motif at position −77. Binding of c-jun/c-fos heterodimers to this sequence confers high levels of expression to the reporter constructs in cultured epidermal keratinocytes, while having little effect in HeLa ...
Objective To investigate the expression of transcription factors including nuclear factor-κB(NF-κB) and activator protein-1(AP-1) in vascular endothelial cells(ECs) in different flow fields,and provide experimental evidence for mechanical signal effects on gene regulation pattern of ECs.Methods Cultur...
序列 该Human Tyrosine Kinase Activator Protein 1 (TKA1) Protein产品的序列以厂家提供的英文说明书为准。来源宿主 大肠杆菌溶解建议 该Human Tyrosine Kinase Activator Protein 1 (TKA1) Protein产品溶解建议以提供的产品说明书为准,详情查看产品说明书。
1. Objective To explore the role of ambroxol in the course of antioxidant therapy in chronic obstructive pulmonary disease(COPD)by investigating its effect on expression of active protein-1(AP-1)and CuZn-superoxide dismutase(CuZn-SOD)in lung of smoking rats. 目的通过研究氨溴索对吸烟大鼠肺组织中...