Activation-induced cell death (AICD) is the process by which cells undergo apoptosis in a controlled manner through the interaction of a death factor and its receptor. Programmed cell death can be induced by a number of physiological and pathological factors including Fas (CD95)-Fas ligand (...
1) activation-induced cell death(AICD) 激活诱导细胞凋亡 1. The significance of activation-induced cell death(AICD) in the persistence hepatitis B virus infection; 激活诱导细胞凋亡(AICD)在乙型肝炎慢性化机制中的意义 2) activation inducing T cell apoptosis ...
activation-induced cell death(AICD) recognition and deletion of T lymphocytes that have been activated and so induced to proliferate. T lymphocytes are activated when a foreign agent is perceived, and AICD thereby prevents them from overgrowth. It is particularly important for regulation of lymphocytes...
摘要原文 A properly functioning immune system is dependent on programmed cell death at virtually every stage of lymphocyte development and activity. This review addresses the phenomenon of activation-induced cell death (AICD) in T lymphocytes, in which activation through the T-cell receptor results in...
Objective To study role of activation-induced cell death (AICD) in the pathogenesis of early renal impairment in chronic hepatitis B patients. 目的 初步研究外周血淋巴细胞激活诱导细胞死亡 (AICD)在慢性乙型肝炎患者早期肾损伤中可能存在的作用。
Activation-induced cell death (AICD) of immune cells is widely believed to be crucial for the regulation of immune responses. Although macrophage apoptosis... Wenxia,Fu,Jinxue,... - 《Cell Research》 被引量: 29发表: 2006年 [The significance of activation-induced cell death (AICD) in pathoge...
Activation-induced cell death (AICD) is involved in peripheral tolerance by controlling the expansion of repeatedly stimulated T cells via an apoptotic Fas... V Mateo,M Menager,G De Saint-Basile,... - 《Blood》 被引量: 87发表: 2007年 Defect in activation-induced cell death in non-obese ...
Activation-induced cell death (AICD) of T lymphocytes can be exploited by cancers to escape immunological destruction. We demonstrated that tumor-specific cytotoxic T lymphocytes (CTLs) and type 1 helper T (TH1) cells, rather than type 2 helper T cells and regulatory T cells, were sensitive ...
change in Bcl-2 mRNA expression in primary murine T cells (Figure 3B). In addition, expression of CD95, TCR, and CD3 on the cell surface was not altered by Dex treatment (data not shown). These results suggest that during the process of AICD, Dex acts upstream of the CD95 death ...
Mutant KRAS (KRASMUT) is often exploited by cancers to shape tumor immunity, but the underlying mechanisms are not fully understood. Here we report that tumor-specific cytotoxic T lymphocytes (CTLs) from KRASMUTcancers are sensitive to activation-induced cell death (AICD). circATXN7, an NF-κ...