Activation-induced cell death (AICD) is the process by which cells undergo apoptosis in a controlled manner through the interaction of a death factor and its receptor. Programmed cell death can be induced by a number of physiological and pathological factors including Fas (CD95)-Fas ligand (...
However, CAR-T cells are less effective on solid tumors mainly due to the weak persistence of CAR-T cells, which might be caused by T cell death. Significant activation-induced cell death (AICD) of CAR-T cells was triggered by repeated antigen stimulation. AICD of T cell is characterized ...
1) activation-induced cell death(AICD) 激活诱导细胞凋亡1. The significance of activation-induced cell death(AICD) in the persistence hepatitis B virus infection; 激活诱导细胞凋亡(AICD)在乙型肝炎慢性化机制中的意义2) activation inducing T cell apoptosis 激活诱导T细胞凋亡...
activation-induced cell death(AICD) recognition and deletion of T lymphocytes that have been activated and so induced to proliferate. T lymphocytes are activated when a foreign agent is perceived, and AICD thereby prevents them from overgrowth. It is particularly important for regulation of lymphocytes...
摘要原文 A properly functioning immune system is dependent on programmed cell death at virtually every stage of lymphocyte development and activity. This review addresses the phenomenon of activation-induced cell death (AICD) in T lymphocytes, in which activation through the T-cell receptor results in...
2) activation-induced cell death (AICD) 活化诱导的细胞凋亡(AICD) 3) Induce differentiation and apoptosis 诱导分化凋亡 4) inducing apoptosis 诱导凋亡 5) apoptosis induction 诱导凋亡 1. A clinical study of Realgar on ATRA-resistant acute promyelocytic leukemia and its effects onapoptosis induction; ...
Ligation of TCRs on stimulated T cells leads to activation-induced cell death (AICD) resulting in the downregulation of immune responses, a process essenti... R Gudi,J Barkinge,S Hawkins,... - 《Oncogene》 被引量: 71发表: 2006年 Siva-1 negatively regulates NF-κB activity: effect on T...
目的 初步研究外周血淋巴细胞激活诱导细胞死亡 (AICD)在慢性乙型肝炎患者早期肾损伤中可能存在的作用。 2. Objective: To investigate the effect of activation-induced cell death (AICD) on cellular immune function in the condyloma acuminatum(CA). 目的研究激活诱导细胞死亡(AICD)对尖锐湿疣患者细胞免疫功能的...
Proliferation and flow cytometry analysis indicated that SEA generated an activation-induced cell death (AICD) phenomenon that was characterized by an increased expression of the chemokine receptor CCR5 on the CD4+/CD45RO+ T cell subset. Incubation of cells with glycoprotein secretion inhibitor ...
Activation-induced cell death (AICD) is a well-known mechanism of peripheral T cell tolerance that depends upon an interaction between Fas and Fas ligand (... N Ishimaru,K Yanagi,K Ogawa,... - 《Journal of Immunology》 被引量: 56发表: 2001年 Engagement of CD44 up-regulates Fas Ligand ...