Activating transcription factor 4 is critical for proliferation and survival in primary bone marrow stromal cells and calvarial osteoblasts. J Cell Biochem. 2008;105(3):885–95.ZHANG X,YU S,GALSON D L,et al.Activating transcription factor 4 is critical for proliferation and survival in primary ...
By using BTG-1 promoter haboring reporter gene and siRNA, activating transcription factor 4 (ATF4) was identified as an essential transcription factor for SAAD-mediated BTG-1 induction. Knock out of BTG-1 gene by CRISPR/Cas9 system decreased the cytotoxicity by SAAD. Furthermore, BTG-1 ...
Activating transcription factor 4 (ATF4) is a member of a family of DNA-binding proteins which includes the AP-1 family of transcription factors, cAMP-response element binding proteins and CREB-like proteins. The ATF4 gene encodes a transcription factor which was initially identified as a widely ...
Activating transcription factor 4 (ATF4), a key mediator of the ISR, and has been reported to induce the expression of genes involved in cellular homeostasis. However, during prolonged activation ATF4 can also induce the expression of pro-death target genes. Therefore, in the present study, we...
Activating Transcription Factor 4 is a stress induced transcription factor that can regulate a multitude of different immune cell responses. The regulation of immunity via ATF4 can be indirect by initiating inflammation that will secrete a cascade of cytokine directed immune responses. In contrast, ATF4...
Their nucleotide sequences revealed that they encode activating transcription factor 4 (ATF4). A full-length cDNA of porcine ATF4 was obtained by the polymerase chain reaction, and its deduced amino acid sequence showed 88 and 83% identity to human and mouse ATF4, respectively. Reverse ...
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ACTIVATING TRANSCRIPTION FACTOR 4 (42-50) [HOMO SAPIENS]/[RATTUS NORVEGICUS]| 基本信息更多信息 中文名称: 中文同义词: 英文名称:ACTIVATING TRANSCRIPTION FACTOR 4 (42-50) [HOMO SAPIENS]/[RATTUS NORVEGICUS] 英文同义词:H2N-KHFKPHGFS-OH;ACTIVATING TRANSCRIPTION FACTOR 4 (42-50) [HOMO SAPIENS]/[RAT...
目的研究银屑病患者皮损内信号转导和转录激活因子4(STAT4)及γ-干扰素(IFN-γ)的表达及其临床意义。 更多例句>> 5) Activating transcription factors 转录激活因子类6) STAT3 转录激活因子3 1. Objective To construct signal transduction and activators of transcription 3 (STAT3) small interference RNA (siRN...
Here, by combining a whole genome shRNA library screen and Master Regulator Inference Algorithm (MARINa) analysis, we identified Transcription Factor Activating Protein 4 (TFAP4) as a novel synthetic lethal interactor with amplification in neuroblastoma. Silencing selectively inhibits amplified neuroblastoma...