Validation of acti- vated caspase-3 antibody staining as a marker of apoptosis in breast cancer. Histopathology 2012; 60: 369-71.Sabine VS, Faratian D, Kirkegaard-Clausen T, et al. Validation of activated caspase-3 antibody staining as a marker of apoptosis in breast cancer[J]....
Activated-Caspase 例句 释义: 全部 更多例句筛选 1. Staining for activated caspase 3 in selected biopsies confirmed the presence of apoptosis. 在选取肾活检的病例中活化半胱天冬酶3染色证实了凋亡的存在。 news.dxy.cn© 2024 Microsoft 隐私声明和 Cookie 法律声明 广告 帮助 反馈...
In extension of these observations we developed a double-immunohistochemical staining procedure which enables the detection of caspase-3-positive apoptotic hepatocytes within glutathione-S-transferase-P (GST-P)-positive preneoplastic liver foci. By use of this technique, inhibition of apoptosis by 2,3...
Other possibilities that might affect cell migration were excluded, including cell death (analyzed by activated caspase-3 staining), aberrant morphology of radial glia (analyzed by Nestin staining), and general brain structure (Figures S1 and 2A–2C; data not shown). Because knockdown of POSH ...
Notably, OGM did not induce apoptosis, as assessed by cleaved caspase 3 levels (Fig. S14G-J).To better understand the mechanisms occurring in the cell after treatment with OGM, we investigated other hallmarks of ferroptosis. Consistent with the elevated CHAC1 levels seen in PDX, U87, and U...
To examine the apoptosis of Mac2-expressing astrocytes, we compared the ratios of triple-positive cells for Mac2, GFAP, and cleaved caspase-3 to double-positive cells for Mac2 and GFAP. Microglia were identified by Iba1 and DAPI staining and oligodendrocytes by APC (cc-1) and DAPI staining...
2,*, Xin Wang2,*, Wenjing Cui1,2,*, Wenwen Wang1,2, Huamei Zhang1, Lu Liu1, Zicheng Zhang1, Zheng Li3, Guoguang Ying1, Ning Zhang1 & Binghui Li1 Cytosolic caspase-3-like proteases, such as caspase-3 and caspase-7, have a central role in mediating the progress of apoptosis. ...
Mitochondrial pathway with activation of caspase-3 is involved in pyroptosis induced by iron. Melanoma A375 cells were pretreated with or without different inhibitors, including NAC (5 mM) or GSH (1 mM) for 2 h, followed by CCCP (20 μM), FeSO4 (100 μM), or CCCP/FeSO4 tr...
We report here that this increase in apoptosis (assessed morphologically by TdT-mediated dUTP nick- end labeling staining) is preceded (24 h of incubation) by inhibition of fatty acid oxidation, by increases in diacylglycerol synthesis, the concentration of malonyl CoA, and caspase-3 activity, ...
days after orthotopic engraftment for proliferation and apoptosis by Ki67 and cleaved caspase 3 immunohistochemical staining, respectively. No significant difference was observed in the proliferation/apoptosis rates, soon after cells injection (day 5, data not shown). Similarly, 2 weeks after engraftment...