Because the vitamin D receptor is expressed in a variety of immune cell types, study into the precise role of this molecule in diseases, notably autoimmune disorders, has been made possible. The physiologically activated version of vitamin D also promotes a tolerogenic immunologica...
aAn important part of the beneficial actions of vitaminD toward T1D is directed against the immune system as demonstrated by the in vitro studies mentioned in the present section. 维生素D的beneficial行动的一个重要部分往T1D被指挥反对免疫系统如是由在当前部分提及的体外研究展示的。[translate]...
Introduction: Vitamin D is a micronutrient that possesses immunomodulatory actions. Higher vitamin D status has been associated with decreased incidence of acute respiratory infections (ARI) in a number of observational studies. However, mechanistic in vitro work investigating effects of vitamin D on the...
Vitamin D is emerging as an important dietary factor that affects the incidence and progression of many malignancies including prostate cancer. The active form of vitamin D, 1,25-dihydroxycholecalciferol [1,25(OH)2D3], inhibits the growth and stimulates the differentiation of prostate cancer...
The Actions of the Vitamin D Receptor in Health and Malignancy; Polymorphic Associations and Gene Regulatory Actions 来自 ResearchGate 喜欢 0 阅读量: 23 作者:M Campbell,K Colston 摘要: The clinical and societal impact of malignancy continues to be highly significant in the developed world and is ...
With regard to non-classical actions, 1,25(OH) 2D 3 has been reported to inhibit the proliferation of a number of malignant cells and to regulate adaptive as well as innate immunity. This article will review new developments related to the function and regulation of vitamin D target proteins...
There is no doubt that vitamin D which is normally formed in skin or obtained in the diet must be altered before it can carry out its functions (DeLuca 1974, 1988). First, 25-hydroxylation is carried out in the microsomes and mitochondria of liver to produce the circulating form of ...
Vitamin D plays a major role in bone mineral homeostasis by promoting the transport of calcium and phosphate to ensure that the blood levels of these ions are sufficient for the normal mineralization of type I collagen matrix in the skeleton. In contrast to classic vitamin D-deficiency rickets,...
Effect of high doses of vitamin D on arterial properties, adiponectin, leptin and glucose homeostasis in type 2 diabetic patients Vitamin D supplementation has the potential to alleviate the cardiovascular damage in diabetic patients. The present study was designed to evaluate long te... A Breslav...
aHigh dose vitamin D should normally be avoided during calcium therapy, to avoid the risk of abnormally high calcium levels. 应该通常避免在钙疗法期间,大剂量维生素D,避免反常地高钙水平的风险。 [translate] a1、相互包容、体谅。凡事多站在对方的角度去思考 1st, contains, the pardon mutually.The ...