Human vitamin K-dependent GAS6: gene structure, allelic variation, and association with stroke. Mu?oz Xavier,Sumoy Lauro,Ramírez-Lorca Reposo,Villar José,de Frutos Pablo García,Sala Núria. Human Mutation . 2004Munoz X,Sumoy L,Ramirez-Lorca R,Villar J,Garcia de Frutos P,Sala N.Human ...
The vitamin K-dependent factors protein S (PROS1) and growth-arrest-specific gene 6 (GAS6) and their tyrosine kinase receptors TYRO3, AXL, and MERTK, the TAM subfamily of receptor tyrosine kinases (RTK), are key regulators of inflammation and vascular response to damage. TAM signaling, which...
Vitamin K1 and vitamin K2 are required for the γ-glutamyl carboxylation of all vitamin K-dependent proteins. Vitamin K has important actions in the nervous system. Vitamin K contributes to the biological activation of proteins Gas6 and protein S, ligands for the receptor tyrosine kinases of the...
Vitamin K1 and vitamin K2 are required for the γ-glutamyl carboxylation of all vitamin K-dependent proteins. Vitamin K has important actions in the nervous system. Vitamin K contributes to the biological activation of proteins Gas6 and protein S, ligands for the receptor tyrosine kinases of the...
Vitamin K‑dependent proteins (VKDPs) are a group of proteins that need vitamin K to conduct carboxylation. Thus far, scholars have identified a total of 17 VKDPs in the human body. In this review, we summarize three important emerging VKDPs: Growth arrest‑specific protein 6 (Gas 6),...
Vitamin K1 and vitamin K2 are required for the γ-glutamyl carboxylation of all vitamin K-dependent proteins[2]. Vitamin K has important actions in the nervous system. Vitamin K contributes to the biological activation of proteins Gas6 and protein S, ligands for the receptor tyrosine kinases of...
*In the category of basic science, contributions cover: VKOR1, the quinone reductases including structure, function and mechanism, vitamin K-dependent carboxylation, the actions of Gas6, vitamin K2-mediated apoptosis and other topics. *In the category of disease-related subjects, contributions cover...
The N-terminal region of each vitamin K-dependent coagulation protein contains from nine to 12 γ-carboxyglutamic acid (Gla) residues. These residues are formed by carboxylation of glutamic acids located within the first 40–45 amino acid residues in the N-terminal region of each protei...
Vitamin K1 and vitamin K2 are required for the γ-glutamyl carboxylation of all vitamin K-dependent proteins. Vitamin K has important actions in the nervous system. Vitamin K contributes to the biological activation of proteins Gas6 and protein S, ligands for the receptor tyrosine kinases of the...
Vitamin K-Dependent Carboxylase is an enzyme that catalyzes the incorporation of carbon dioxide into specific glutamic acid residues of proteins, a process essential for the activation of vitamin K-dependent proteins. AI generated definition based on: Encyclopedia of Biological Chemistry (Second Edition)...