One type of skeletal muscle fibers, known as slow fibers, subserves tonic functions, including posture. When the end plate potential (EPP), generated at the neuromuscular junction, reaches threshold for eliciting an AP in the skeletal muscle fiber, an AP is propagated down the muscle fiber in...
A. has a prolonged plateau phaseB. spreads inward to all parts of the muscle via the T tubulesC. causes the immediate uptake of Ca2+ into the lateral sacs of the sarcoplasmic reticulumD. is longer than the action potential of cardiac muscleE. is not essentialfor contraction 相关知识点: ...
The greater the diameter of the axon, the lower is the resistance of the axoplasm and the further is the electrotonic spread of potential. Conduction is therefore more rapid in large fibres and in these the nodes are more widely spaced. The A α axons that innervate skeletal muscle have ...
THE development of the action potential mechanism has been studied during the differentiation of myoblasts into cross-striated muscle fibres. A clonal line of muscle cells isolated from rat thigh was usedbecause this provides a homogeneous population of cells easily accessible for electrophysiological ...
The Ca-activated Clchannel (CaCC) TMEM16A/Anoctamin 1 (ANO1) is expressed in gastrointestinal epithelia and smooth muscle cells where it mediates secretion and intestinal motility. However, ANO1 Clconductance has never been reported to play a role in skeletal muscle. Here we show that ANO1 is...
In rat muscle, nearly 90% of the fibers showed CaAPs, which were not affected by the cut-end condition. Human and rat muscle fibers had similar membrane potential and conductance in the resting state. In human muscle (22–32± C, 84 mM Ca), the threshold and peak potential during a ...
The neuromuscular junction: (a) is the junction between a motor neuron and a skeletal muscle fiber (b) transmits an action potential between the nerve cell and muscle cell on a one-to-one basis (c) may produce either an EPSP or an IPSP on t...
‘neuronal membrane’, this description applies to activity found in some plant cells and other parts of mammal physiology, for example, in skeletal muscle cells, or, more generally, in cells that possess gated channels for responding selectively to changes in membrane potential. For this reason,...
Explain briefly why the action potential of cardiac muscle is significantly longer than skeletal muscle. Explain function of skeletal muscle and how its cell supports the skeletal muscle function. Why is calcium important for muscle functioning? Give details....
signals are not bigger. Thus, for example, you will not feel a greater sensation of pain, or have a stronger muscle contraction, because of the size of the action potential because they are not different sizes. As we have seen, the depolarization and repolarization of an action potential ...