Disruption of action potential and calcium signaling properties in malformed myofibers from dystrophindeficient mice. Erick O.Hern andez-Ochoa1,Stephen J.P.Pratt,Karla P.Garcia-Pelagio et al. Physiol Rep . 2015Hernandez-Ochoa EO, Pratt SJ, Garcia-Pelagio KP, Schneider MF, Lovering RM. ...
Optical Mapping Action Potentials Calcium Transients Mouse Heart Cardiovascular Studies Fluorescence Imaging Genetic Engineering Physiological Phenotyping Transmembrane Potential Vm Excitation contraction Coupling Langendorff Perfused Mouse Hearts Heart Failure
Here, we examined myofiber excitability using high-speed confocal microscopy and the voltage-sensitive indicator di-8-butyl-amino-naphthyl-ethylene-pyridinium-propyl-sulfonate (di-8-ANEPPS) to assess the action potential (AP) properties. We also examined AP-induced Ca2+ transients using high-speed ...
Inotropic and energetic effects of altering the force-calcium relationship: mechanisms, experimental results, and potential molecular targets. J Cardiac Fail 6... MAP Koretsky - 《Journal of Cardiac Failure》 被引量: 82发表: 2000年 The interrelationship of calcium-mediated action potentials and tensi...
When the presynaptic membrane is depolarized by an action potential, the calcium voltage-gated channels open. This leads to an influx of calcium, which changes the state of certain membrane proteins in the presynaptic membrane, and results with exocitosis of the neurotransmitter in the synaptic ...
Citation and Abstract Advanced search Article outline is loading... Journal of Molecular and Cellular Cardiology Volume 23, Supplement 4, June 1991, Pages S32 Program and Abstracts of the 8th G.R.R.C Meeting About ScienceDirect Contact and support Information for advertisers Terms and cond...
Calcium component to action potentials in rat pars intermedia cells.1. The ionic dependence of the action potential of rat pars intermedia cells was investigated by using intracellular recording techniques. 2. In the presence of tetrodotoxin (TTX, 5 x 10(-6)M), the action potentials evoked by...
It is suggested that α 2 -adrenoceptors mediate the inhibition of voltage-dependent Ca 2+ entry during the action potential. 展开 关键词: Parasympathetic neuron Calcium-dependent action potential Norepinephrine α 2-Adrenoceptor Inhibition DOI: 10.1016/0168-0102(88)90022-3 ...
No alterations in the magnitude and voltage dependence of inward rectifier ( I Kl ) were found around the resting membrane potential. The diabetes-related suppression of I to explains the decreased repolarization rate of action potentials. 展开 ...
These include IA and ID potassium currents, steady-state “persistent” sodium current, T-type calcium current, and the hyperpolarization-activated cation current called Ih. The system of ionic currents that controls action potential shape and firing patterns in central neurons, although complex, has...