However, the 225Ac radionuclide presents multiple daughter nuclides in its decay chain, which can escape the targeted site, circulate in plasma, and cause toxicity in areas such as kidneys and renal tissues. Several ameliorative strategies have been devised to circumvent t...
TerraPower Isotopes is bringing the next generation of isotopes to market using a natural decay method to produce Actinium-225 free of isotopic impurities. This method increases the efficiency and automation of the process, which enables TPI to produce a significant, consistent supply of the isotope...
A computer code based on the generalized Bateman equations has been developed to allow calculations of the amounts of any isotope in the 229Th decay chain as a function of recoil separation exposure time and elapsed time after the separation. An excellent match has been obtained between the ...
"This trial is an exciting evolution of our Actimab-A program and application of the isotope Actinium-225. Actinium-225 is a potent medical isotope that can kill a cancer cell with a single alpha particle hit, emits four alpha particles in its...
Stability studies showed that colloidal structure also retained free daughter radionuclides formed by the 225Ac decay chain. 225Ac tin colloids could be ideal nanocarriers for localized cell killing due to high linear energy transfer and prevention of free radioisotope daughters.Davut CakiciBenan Kilbas...
(1/2) = 9.9 days) has found significant promise for therapeutic use due to its long half-life and extensive decay chain that yields four alpha particles.2 A fundamental challenge in the widespread use of this radionuclide, however, is the lack of a suitable chelating agent that can stably ...
The yield for 221Fr approached 50% while that for 213Bi approached 99%.; It was found that the activity of 221Fr on the collector plate could be calculated by multiplying the chain decay equation by a geometry correction factor of the form: ...
are too short-lived to accumulate in macroscopic quantity. Actinium-227, which is one of the decay products ofuranium-235, has a 21.8-yearhalf-lifeand in turn decays almost entirely tothorium-227, but about 1 percent decays tofrancium-223. This whole disintegration chain with its branches is...