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microfilaments that are associated with the are important for generating these specializations, and also provide the driving force for remodelling cell morphology and triggering new cell when the environment is modified. This phenomenon is achieved through a tight coupling between cell structure and ...
& Wolf, K. Plasticity of cell migration: a multiscale tuning model. J. Cell Biol. 188, 11–19 (2010). CAS PubMed PubMed Central Google Scholar Tomasek, J. J. & Hay, E. D. Analysis of the role of microfilaments and microtubules in acquisition of bipolarity and elongation of ...
often found just beneath the plasma membrane, where they crosslink to form the cell cortex. Actin filaments are used to change the shape of the plasma membrane, moving it outwards in projections or inwards in invaginations. Whereas discrete bundles of...
Cell - Actin Filaments, Cytoskeleton, Proteins: Actin is a globular protein that polymerizes (joins together many small molecules) to form long filaments. Because each actin subunit faces in the same direction, the actin filament is polar, with different
Tropomyosin also binds to F-actin in smooth muscle and in non-muscle cells and stabilizes and regulates the filaments there in the absence of troponin6. Although crystal structures for monomeric actin (G-actin) are available7, a high-resolution structure of F-actin is still missing, hampering...
Recent development of innovative tools for live imaging of actin filaments (F-actin) enabled the detection of surprising nuclear structures responding to various stimuli, challenging previous models that actin is substantially monomeric in the nucleus. W
In other cell types actin assembles into a variety of structures including isotropic networks of filaments within the cytoskeleton, contractile actin filament bundles often called stress fibers, highly organized parallel arrays of filaments in such structures as microvilli and the thin protrusions of ...
摘要: The front of motile cells is thought to be pushed out by branched filaments of actin protein abutting the cell membrane. New work challenges this textbook view, showing that actin branches grow away from, or obliquely to, a surface.关键词:...
(Lp,Figure 3) are the structural component of the sheet-like protrusions at the cell periphery called ‘lamellipodia’ (or ruffles, when they fold upwards). The body of the cell is pervaded by a loose network of actin filaments, a proportion of which are organized into prominent bundles, ...