The previous work has defined cholesterol bioflux via lipoprotein/receptor route is the gastric cancer (GCa) prognosis biosignature. The prognosis importance of acetyl‐CoA to cholesterogenesis (mevalonate pathway) in GCa is yet to be defined. Using Kaplan–Meier Plotter web‐based gene survival ...
Acetyl-CoA C-AcyltransferaseCoronary ArteriosclerosisIndoleacetic Acids冠状动脉硬化吲哚乙酸类BACKGROUND: The enzyme acyl-coenzyme A:cholesterol acyltransferase (ACAT... SE Nissen,EM Tuzcu,HB Brewer,... - 《N Engl J Med》 被引量: 1274发表: 2006年 ACAT Inhibition and Progression of Carotid Atheroscle...
5.1Acetyl-CoA to mevalonic acid (Figure 10.7) ACAT2is the firstenzymein thecholesterol synthesispathway, catalysing the conversion of two molecules of acetyl-CoA toacetoacetyl-CoA. HMG-CoAsynthase(HMGCS) acts next, requiring water to condense acetyl-CoA with acetoacetyl-CoA to form HMG-CoA. Cyt...
The condensation of acetyl-CoA units into acetoacetyl-CoA. In the last few years, it has been demonstrated by this group and others that rat liver peroxisomes participate in cholesterol synthesis. It has been shown... SL Thompson,SK Krisans - 《Journal of Biological Chemistry》 被引量: 142...
The basis for the elucidation of thisisoprenoidbiosynthesispathway was the discovery by Konrad Bloch (USA; 1964, Nobel Prize, Medicine) thatacetyl-CoAis a precursor for the biosynthesis of steroids. The biosynthesis of the intermediary productIPPstarts with two molecules of acetyl-CoA to produceaceto...
Acetyl-CoA Carboxylase 2 Acetyl-Coa Carboxylase-Alpha acetyl-CoA deacylase acetyl-CoA hydrolase acetyl-CoA ligase acetyl-CoA pathway acetyl-CoA synthetase acetyl-CoA thiolase Acetyl-CoA-Carboxylases acetyl-CoA:alpha-glucosaminide acetyltransferase
Acetyl-CoA carboxylases (ACCs) play a rate-limiting role in fatty acid biosynthesis in plants, microbes, mammals and humans. ACCs have the activity of both biotin carboxylase (BC) and carboxyltransferase (CT), catalyzing carboxylation of Acetyl-CoA to malonyl-CoA. In the past years, ACCs have...
AT-1/SLC33A1 is a key member of the endoplasmic reticulum (ER) acetylation machinery, transporting acetyl-CoA from the cytosol into the ER lumen where acetyl-CoA serves as the acetyl-group donor for Nε-lysine acetylation. Dysfunctional ER acetylation, a
Cholesterol is synthesized in chicken through de novo lipid biosynthetic pathway where two most important genes viz. SREBP1 and ACACA play immense role. To minimize cholesterol synthesis, RNAi approach was adopted and accordingly, we developed transgenic
Which of the following options is correct? Similar to amino acid alanine (except for one amino group), the molecule by which alanine can enter the catabolic pathway is a. Acetyl CoA b. Glucose-6-phosphate c. Pyruvic acid What is the name of the aerobic pathway that produces 2 ATP molecul...