Acetyl-CoA synthetase 2 (ACSS2), an important member of the acetyl-CoA synthetase (ACSS) family, can catalyze the conversion of acetate to acetyl coenzyme A (acetyl-CoA). Currently, acetyl-CoA is considered an important intermediate metabolite in the metabolism of energy substrates. In addition...
It is of special significance to decipher the role acetyl-CoA synthetase short chain family (ACSS) in cancer cells confronting metabolic stress. Here we analyzed the generation of lipogenic AcCoA in bladder cancer cells under metabolic stress and found that in bladder urothelial carcinoma (BLCA) ...
A simple radiochemical method is described for the assay of acetyl-CoA synthetase utilizing C 14-labeled acetate. Enzyme activity is followed by the measurement of direct incorporation of C 14-labeled acetate into acetyl CoA. Separation of the C 14-labeled reactant from its reaction product is ...
ACSS1 acyl-CoA synthetase short chain family member 1 ACSS2 acyl-CoA synthetase short chain family member 2 AML acute myeloid leukemia AMPK AMP-activated protein kinase ATP adenosine triphosphate BC biotin carboxylase BCAA branched-chain amino acids BCCP biotin carboxyl carrier protein BCL2 B-cell ...
It is of special significance to decipher the role acetyl-CoA synthetase short chain family (ACSS) in cancer cells confronting metabolic stress. Here we analyzed the generation of lipogenic AcCoA in bladder cancer cells under metabolic stress and found that in bladder urothelial carcinoma (BLCA) ...
Acetyl-CoA synthetase (ACS) plays a key role in microalgal lipid biosynthesis and acetyl-CoA industrial production. In the present study, two ACSs were cloned and characterized from the oleaginous microalga Chromochloris zofingiensis. In vitro kinetic analysis showed that the K-m values of CzACS...
A novel octameric AMP-forming acetyl-CoA synthetase from the hyperthermophilic crenarchaeon Pyrobaculum aerophilum. FEBS Lett. 579:477-482.C. Bra¨sen, C. Urbanke, and P. Scho¨nheit, "A novel octameric AMP-forming acetyl-CoA synthetase from the hyperther- mophilic crenarchaeon Pyrobaculum ...