TLR4和AGER是HMGB1研究最深入的两种受体,它们通过激活NF-κB和干扰素调节因子3(IRF3)途径介导HMGB1在多个免疫细胞中的活性,从而产生促炎细胞因子和趋化因子。HMGB1与巨噬细胞和中性粒细胞上表达的髓细胞触发受体1(TREM1)结合也可以通过NF-κB途径诱导细胞因子的产生,而CD24...
目的:探讨急性胰腺炎患者血清前白蛋白(PAB),高迁移率族蛋白B1(HMGB1),可溶性白介素2受体(SIL-2R),紧张素转化酶2(ACE2)水平变化及意义.方法:选择2018年7月至2020年7月于我院进行治疗的急性胰腺炎患者83例患者进行研究,设为病例组,并选择我院同期体检健康者70例作为对照组,分析患者血清PAB,HMGB1,SIL-2R,ACE...
猪高迁移率族蛋白B1(HMGB1)ELISA试剂盒,是科学研究中不可或缺的工具。该试剂盒采用双抗夹心法,能准确检测尿液、组织、细胞上清等样本中的HMGB1含量,有效期长达6个月。现在店内瑞清品牌的HMGB1试剂盒,有效成分含量高达99%,性能稳定,且支持加工定制,满足您多样化的实验需求。店内还提供顺丰包邮和技术支持,确保您使用...
Increased levels of the circulating inflammatory and/or nociceptive molecules like HMGB1, NLRP3, and IL-6 may play a role in the potential induction of the trigeminal system and manifestation of headache secondary to SARS-CoV-2 infection.
The first step is to target angiotensin-converting enzyme (ACE2) in the acute phase. The second step is to target high mobility group box 1 (HMGB1) molecule in the exacerbatory phase. The last step is to target heat shock protein (HSP) 47 in the fibrosing phase. The steps were used ...
867. Conclusion: The expression of PAB, HMGB1, sIL-2R and ACE2 in serum was closely correlated with ApacheII score, which had a high predictive value for acute pancreatitis.杨旭辉夏杏芳周志林梅勇戴军Progress in Modern Biomedicine