HMGB1-IN-2 (compound 15) 是一种针对高度保守的核蛋白 HMGB1 的抑制剂,其在 RAW264.7 细胞中展现出 NO 抑制活性,IC50 为 20.2 μM。 HMGB1-IN-2 (30 μM) 能够减少 IL-1β、TNF-α、caspase-1 p20 的表达,并抑制 NF-κB p65 的磷酸化作用,显示出抗凋亡特性。在脓毒症急性肾损伤模型的小鼠中,HMGB...
Deng, "Expression of HMGB1 and HMGN2 in gingival tissues, GCF and PICF of periodontitis patients and peri-implantitis," Archives of Oral Biology, vol. 56, no. 10, pp. 1106-1111, 2011.EXPRESSION OF HMGB1 AND HMGN2 IN GINGIVAL TISSUES, GCF AND PICF OF PERIODONTITIS PATIENTS AND PERI-...
In addition, our in vitro experiments demonstrated that HMGB1 induced proliferation and PCNA expression in CT26 colon cancer cells through the ERK1/2 pathway. Conclusion GSDME-mediated pyroptosis promotes the development of CAC by releasing HMGB1, which induces tumor cell proliferation and PCNA ...
Note: the hmgb1-1, 2, 4, 5, 6, 7 reverse primers in the same 翻译结果4复制译文编辑译文朗读译文返回顶部 Note: hmgb1-1, 2, 4, 5, 6, and 7 reverse primer same 翻译结果5复制译文编辑译文朗读译文返回顶部 Note: hmgb1-1, 2, 4, 5, 6, 7 directs the phase reverse with ...
GW could up-regulate expression of Cathepsin B (CTSB), and inhibition of CTSB blocked GW-induced HMGB1 degradation. In summary, all the data showed that activation of CB2R could promote the intracellular degradation of HMGB1 via the autophagy-lysosome pathway in macrophage....
aTax及其突变体未影响Jurkat细胞中HMGB1基因mRNA的表达,Jurkat、MT-4、MT-2细胞中HMGB1基因mRNA的表达量相似。 Tax and the mutant have not affected in the Jurkat cell HMGB1 the gene mRNA expression, Jurkat, MT-4, in the MT-2 cell HMGB1 the gene mRNA expression quantity are similar.[translate]...
2013. Simvastatin suppresses vascular inflammation and atherosclerosis in ApoE(-/-) mice by downregulating the HMGB1-RAGE axis. Acta. Pharmacol. Sin. 34(6... M Liu,Y Yu,H Jiang,... - 《Acta Pharmacologica Sinica》 被引量: 0发表: 2013年 Physiological and pathophysiological outcomes of the ...
Luo L, Xie P, Gong P, Tang XH, Ding Y, Deng LX: Expression of HMGB1 and HMGN2 in gingival tissues, GCF and PICF of periodontitis patients and peri-implantitis. Arch Oral Biol 2011, 56:1106-1111.L. Luo, P. Xie, P. Gong, X.-H. Tang, Y. Ding, and L.-X. Deng, "...
Expression of HMGB1, TLR2 and TLR4 in livers of infants with biliary atresia (BA) and in bile ducts of mice challenged with RRV.Yinrong QiuJixin YangWenmei WangWentao ZhaoFei PengYing XiangGang ChenTao ChenChengwei ChaiShuaiyu Zheng
Both HMGB1 and HMGB2 were expressed in the nucleus and cytosol of papillary carcinoma. In the clear cell carcinoma of this case, HMGB1 expression was stained both in the nucleus and cytosol, while HMGB2 was observed in the nucleus, but not in the cytosol. More samples need to be further ...