技术标签:blastpNCBI NCBI推出blastp加速服务(Accelerated protein-protein BLAST) 很多时候会用到NCBI在线blastp的nr库,随着nr库越来越大,速度也越来越慢。这不在今年5月份的时候推出了blastp加速工具。使用非常简单,blastp页面中在Program Selection一项中选择Quick BLASTP(见下图)。现在已经是默认选项。... ...
Evolution of novel traits is a challenging subject in biological research. Several snake lineages developed elaborate venom systems to deliver complex protein mixtures for prey capture. To understand mechanisms involved in snake venom evolution, we decoded here the ~1.4-Gb genome of a habu,Protobothrop...
Indicates new application POPULAR GPU‑ACCELERATED APPLICATIONS CATALOG | May17 | 17 CUDASW++ CUSHAW G-BLASTN GPU-Blast * Huygens mCUDA-MEME * Microvolution MUMmer GPU NVBIO NVBowtie PEANUT REACTA * RELION-2 SeqNFind Open source software for Smith-Waterman protein database searches on GPUs....
Protein clustering of up to tens of billions of proteins Frameshift alignments for long read analysis. Low resource requirements and suitable for running on standard desktops or laptops. Various output formats, including BLAST pairwise, tabular and XML, as well as taxonomic classification. ...
a genome size of approximately 1.1 Gb with 48,836 protein-coding genes (DOE-JGI). Thus, three de novo assemblies for finger millet (Table6) are available on NCBI and Phytozome. GWAS in finger millet has made significant progress due to the availability of these three available genomes allowin...
Gleevec (imatinib mesylate), a highly promising new drug for the treatment of chronic myelogenous leukemia in blast crisis, in accelerated phase, and in chronic phase after interferon failure or intolerance, received orphan drug status from the U.S. Food and Drug Administration (FDA) Office of ...
SF3B1mutation causes multiple alterations in mRNA processing. The use of alternative 3′ or 5′ splice site produces transcripts containing short intronic sequences that are degraded by the non-sense mediated decay (NMD) or are translated into a variant protein9,10,11. These splicing changes driv...
In naïve mice, cyanocobalamin treatment enhanced the expression of fibronectin type 3 domain-containing protein (P < 0.01) and serine/threonine transporter SstT (P < 0.05), along with favoring numerous notable genes: type 2 toxin-antitoxin system HicB family antitoxin, flagellin domain protein,...
It preserved the integrity of the intestinal barrier by regulating the tight junction protein ZO-1 and claudin-1. The tumor necrosis factor-α and interleukin-6 were reduced by LZZAY01. The abundance and diversity of the intestinal microbiota were enhanced, especially the beneficial bacterial ...
In the last step, blastx (E-value < 0.00001) was employed to search for homologues of our assembled unigenes in protein databases such as NR, Swiss-Prot, KEGG and COG. The best results were used to determine the sequence orientations of the unigenes. If results from different ...