41 Thus, it is possible that reduction of serum glutamate levels is due to activating effects of acamprosate on GS in the liver. In addition, a reduction of the serum glutamate/glutamine ratio in response to acamprosate is consistent with a reduction in glutamate levels in response to ...
1B). HSD11B1 converts cortisone to cortisol, a major “stress hormone” that is highly expressed in the liver (Dodd et al., 2022, Morgan et al., 2014). This enzyme has been known to play a role in alcohol-related liver disease (ALD) (Ahmed et al., 2008, Stefan et al., 2014)...