Acamprosate - Uses, Side Effects, and More Medically Reviewed by Laurel Riemann, PharmD on Aug 28, 2024 | Written by Thomas S. Franko, PharmD Common Brand Name(s): Campral Common Generic Name(s): acamprosate, acamprosate Ca, acamprosate calcium Pronunciation: a-KAM-pro-sate Drug Classes:...
Acamprosate (calcium-acetyl homotaurinate) is a synthetic derivative of taurine that is used to treat relapse in alcohol-dependent patients. It is also effective in animal models of alcoholism. Acamprosate suppresses the ADE in two-bottle choice and operant self-administration designs. It has also...
Acamprosate, calcium acetyl homotaurinate, was first developed and tested in the early 1980s in France and has been available in the USA since 2004. Its major mechanism of action is the reduction of cerebral hyperexcitability by interacting with glutamate receptors. More than 20 randomized, ...
Available as acamprosate calcium; dosage expressed in terms of the salt.AdultsAlcohol DependenceMaintenance of Abstinence of Alcohol Ingestion Oral 666 mg 3 times daily.A lower dosage (1.3 grams daily given in 3 unequally divided doses of 666, 333, and 333 mg) also evaluated in clinical ...
which is present in an amount of 5 to 20% by weight of the dosage form, without any coating.;EFFECT: invention enables to administer to a patient large doses of calcium acamprosate when eating/fasting, while simultaneously avoiding side effects in the gastrointestinal tract.;3 cl, 4 dwg, ...