It is widely accepted that oxidative stress plays a central role in diabetes-induced renal injury. Prolonged hyperglycemia causes excess glucose to contact and react with proteins and lipids resulting in advanced glycation end-products (AGEs), which are known to cause multiple complications in diabetic...
Figure 6.Lipids are absorbed by diffusion after digestion to monoacylglycerols and fatty acids. These are reconstituted into triacylglycerols and packaged as chylomicrons within the cell before entering intravillous lymphatic vessels (lacteals); these have an open endothelium (broken outline) and are ...
absorption of small nutrient molecules. Molecules ofcarbohydrates,proteins, orlipids, however, are too large and complex to move easily across cell membranes. Bacteria and fungicircumventthis by secreting digestive enzymes onto the food material; these enzymes catalyze the splitting of the large ...
Methionine restriction alleviates high-fat diet-induced obesity: involvement of diurnal metabolism of lipids and bile acids. Biochim. Biophys. Acta Mol. Basis Dis. 1866, 165908 (2020). Article CAS PubMed Google Scholar Suriano, F. et al. Novel insights into the genetically obese (ob/ob) ...
Reinforcement of the intestinal mucosal barrier via mucus-penetrating PEGylated bacteria Article 05 June 2024 Intestinal miRNAs regulated in response to dietary lipids Article Open access 03 November 2020 The manganese transporter SLC39A8 links alkaline ceramidase 1 to inflammatory bowel disease Art...
The following statement is completely sacrilegious, but to keep things simple, think of a lipid as a synonym for a fat (but technically… fat, as well as phospholipids, waxes, sterols, fat-soluble vitamins, triglycerides, and others are actually subcategories of lipids). ...
Molecular mechanisms of dietary retinyl ester digestion are reviewed. Mechanisms of intestinal absorption of carotenoids and vitamin A are reviewed. A nu... EH Harrison - BBA - Molecular and Cell Biology of Lipids 被引量: 234发表: 2012年 Genes and intestinal absorption of lipidic microconstituents...
1 one requires sets of parameters defining the membrane geometry, microscopic partition coefficients between aqueous vehicle, lipid and corneocyte; SC and epidermis; and epidermis dermis (Klip/w, Kcor/w, Kepi/SC and Kder/epi) and diffusion coefficients within lipids, corneocytes, epidermis and ...
apoB-48 provides structure to the nascent chylomicron, while apoA-IV, apoA-I, and apoC-III function in the periphery to modify plasma lipid metabolism and clearance, interact with inflammatory apparatus for efficient clearance of dietary lipopolysaccharide and oxidized lipids, and modulate insulin ...
Chen et al., “Peptide Drug Permeation Enhancement by Select Classes of Lipids”, presented at the 45th American Society of Cell Biology, S.F., CA, Dec. 10-14, (2005). Edwards CM., “GLP-1: target for a new class of antidiabetic agents?”, J. R. Soc. Med., 97(6):270-274...