Potassium (K) is the most abundant cation in humans and is essential for normal cellular function. Alterations in K regulation can lead to neuromuscular, gastrointestinal, and cardiac abnormalities. Dyskalemia (i.e., hypokalemia and hyperkalemia) in heart failure is common because of heart failure...
Subjects with heart failure may show hyponatremia, magnesium, and potassium deficiencies; the latter two play a pivotal role in the development of cardiac arrhythmias. The early identification of these alterations and the knowledge of the pathophysiological mechanisms are very useful for the management ...
- Hyponatremia: Low sodium levels; can be caused by conditions like heart failure, liver disease, or kidney disorders. - Hypernatremia: High sodium levels; can occur in cases of dehydration or excess sodium intake. - Hypokalemia: Low potassium levels; can result from conditions like diuretic us...
- 《Rheumatology Advances in Practice》 被引量: 0发表: 2024年 Diuretics Adverse effects of thiazide diuretics include fluid and electrolyte imbalances, impaired glucose tolerance, and lipid abnormalities. The aldosterone antagonist spironolactone is a weak diuretic and is primarily used for its potassium...
Serum potassium concentrations can be altered as potassium shifts between the tissue and plasma compartments secondary to drug actions. In addition, drugs have been shown to interfere with the normal physiological functioning of the kidney with respect to potassium homeostasis, as well as the renin-...
suggesting an impaired signal transduction was involved in the pathogenesis of DCM.88 The second group consists of mutations affecting ion channel function; regulatory subunit of ATP-sensitive potassium channel (ABCC9)89 and cardiac sodium channel (SCN5A).90 Clinical pheno- types of ABCC9 and SCN5...
The human Purkinje Trovato2020 model was also able to reproduce the effects of potassium and calcium channel block on repolarization properties, as well as sodium channel block on electrical propagation. The simulation results were in agreement with human experimental data acquired at several frequencies...
It is well known that changes in serum potassium cause ventricular arrhythmias as a result of clearly documented changes in the electrophysiological charac... LS Gettes - 《Circulation》 被引量: 181发表: 1992年 Serum electrolyte abnormalities secondary to Fleet's Phospho-Soda colonoscopy prep The ...
potassium channel, which carries the rapid delayed rectifier current (IKr) in the heart. However, the proarrhythmic risk associated with drugs that block hERG can be modified in patients by a range of environmental- and disease-related factors, such as febrile temperatures, alterations in pH, dy...
Available collected blood tests from the time of imaging, including hemoglobin, urea reduction ratios, albumin, C-reactive protein, phosphate, parathyroid hormone, glucose, predialysis creatinine and potassium, lipid profile, as well as each HD participant’s medical and dialysis history including ...