Adult patients with sickle-cell disease (SCD) often have multiple bone compactions causing tissue hypoxia and osteonecrosis. The impact on bone abnormalities lesion detected by bone mass density is not well defined.TaysirSalmaniyaS.Salmaniya
With the aging of the population, the incidence of osteoporosis (OP) is on the rise, but the ecology of immune cell subpopulations in OP is poorly understood. Therefore, identifying cell subpopulations involved in promoting the development of OP may faci
Kim A, Economidis MA, Stohl HE. Placental abruption after amnioreduction for polyhydramnios caused by chorioangioma. BMJ Case Rep. 2018;2018.https://doi.org/10.1136/bcr-2017-222399 Kimball JW. Organizing the Embryo: the central nervous system. Biology Pages, last modified May. 2011;17.http:...
We first detected alterations in PDGFR-β levels in the subchondral bone of humans with OA. Western blot results showed that the PDGFR-β level was remarkably elevated in the osteoarthritic part of the human subchondral bone compared with the relatively normal (RN) part (Fig.1a, b).7This ele...
Furthermore, the encapsulation did not result in any changes of organoid structural morphology. Using a biomaterial to modulate collagen expression allows for a prolonged kidney organoid culture in vitro and a reduction of abnormal type 1a1 collagen expression bringing kidney organoids closer to ...
Reduction in cav-1 or a dominant-negative mutant of cav-1 can reduce BMPR II plasma membrane localization, decreased BMP- dependent Smad phosphorylation and gene regulation [49]. We also found that cav-1 was downregulated in MCT treated rats, which may promote the formation of PAH through ...
Abnormal Alternative content
After 6 months, the bone mass stabilized. Conclusions: The vitamin D metabolism remains disturbed for a considerable time after renal transplantation. In nearly half of the patients, the levels of active vitamin D remain abnormal for at least 6 months. The BMD decreased during the first 6 ...
Abnormal distal renal tubular acidification in patients with low bone mass: prevalence and impact of al- kali treatment. Urolithiasis. 2016.Sromicki JJ, Hess B. Abnormal distal renal tubular acidification in patients with low bone mass: prevalence and impact of alkali treatment. Urolithiasis. 2017...
In 1978, the term 'monoclonal gammopathy of undetermined significance' (MGUS) was established by Kyle [3]. MGUS is defined as a serum M protein <30 g/L; <10% plasma cells in the bone marrow, if done; little or no M protein in the urine; nonexistence of lytic bone lesions, anaemia,...