Abnormal vitamin D metabolism and loss of bone mass after renal transplantation. Nephron Clin Pract 2003;93:C21-8.De Sevaux RG,Hoitsma AJ,Van Hoof HJ,et al.Abnormal vitamin D metabolism and loss of bone mass after renal transplantation. Nephron . 2003...
Specifically, the top and bottom 1% of cells based on feature number were filtered out, as well as cells with a mitochondrial gene expression ratio exceeding 10%. After quality control, the cells were clustered using the Seurat package31,followed by dimensionality reduction and visualization using ...
Delay of puberty leads to psychological problems, secondary to short stature and/ or delay in the acquisition of secondary sex characteristics and the reduction of bone mass. Although the final height in patients with CDGP is usually normal, some of these patients do not reach the third ...
Iron is one of the important trace elements in life activities. Abnormal iron metabolism increases the incidence of many skeletal diseases, especially for osteoporosis. Iron metabolism plays a key role in the bone homeostasis. Disturbance of iron metabolism not only promotes osteoclast differentiation an...
Platelet dysfunction plays a critical role in the pathogenesis of inflammatory bowel disease (IBD). Despite clinical observations indicating abnormalities in platelet parameters among IBD patients, inconsistencies persist, and these parameters lack stand
(Fig.4c–fand Fig.S4c–f). Flow cytometry analysis also revealed a significant reduction in the number of MSCs (CD45−CD31−Sca1+CD24+) in the bone marrow of the PDGFR-β−/−mice relative to the littermate controls after ACLT (Fig.4g, h).40,41Consistently, a reduction in ...
of birth, ZFP521Δ/Δ mice displayed significant weight reduction as they grew, and most of them died before 10 weeks of age. They displayed abnormal behavior, such as hyper-locomotion, lower anxiety and impaired learning, which correspond to the symptoms of schizophrenia. The border of the ...
Kim A, Economidis MA, Stohl HE. Placental abruption after amnioreduction for polyhydramnios caused by chorioangioma. BMJ Case Rep. 2018;2018.https://doi.org/10.1136/bcr-2017-222399 Kimball JW. Organizing the Embryo: the central nervous system. Biology Pages, last modified May. 2011;17.http...
Reduction in cav-1 or a dominant-negative mutant of cav-1 can reduce BMPR II plasma membrane localization, decreased BMP- dependent Smad phosphorylation and gene regulation [49]. We also found that cav-1 was downregulated in MCT treated rats, which may promote the formation of PAH through ...
We also found a marked reduction of α -granule cargo and membrane proteins in mature megakaryocytes from #1 and #2 GPS patients compared to controls. These results are consistent with previous findings in the bone marrow biopsies of GPS patients15,31,32 and in the bone marrow of two Nb...