Drug-drug interactions (DDIs) can lead to reduced treatment efficacy or increased toxicity. This retro-prospective study aimed to evaluate outcomes, DDIs' impact, and toxicities of abemaciclib combined with endocrine therapy in a real-world setting. Patients from 12 referral Italian hospitals with ...
This report displays the potential drug interactions for the following 2 drugs:abemaciclib cholera vaccine, liveEdit list (add/remove drugs) Consumer Professional Interactions between your drugsMajor cholera vaccine, live abemaciclib Applies to: cholera vaccine, live and abemaciclib If you are ...
Drug and food interactions Moderate abemaciclib food Applies to: abemaciclib Grapefruit juice can increase the blood levels of abemaciclib. This may increase side effects such as nausea, vomiting, diarrhea, abdominal pain, decreased appetite, mouth sores, blood clots, hair loss, liver problems, and...
Abemaciclib has minor interactions with no other drugs This information does not contain all possible interactions or adverse effects. Visit the RxList Drug Interaction Checker for any drug interactions. Therefore, before using this product, tell your doctor or pharmacist about all your products. Keep...
Does Verzenio interact with other medicines (drug interactions)? Always tell your healthcare provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. In particular, make sure you discuss if you are using any of...
and a predominant route of elimination by drug metabolism.36Toxicology and clinical data suggest that adavosertib has drug-drug interactions withCYP3A4substrates (likeondansetronor ciprofloxacin) that possibly prolong the QT interval as measured by electrocardiogram. A phase I trial of a radiotherapy-...
Spectrum and degree of CDK drug interactions predicts clinical performance. Mol. Cancer Ther. 15, 2273–2281 (2016). Article ADS PubMed Google Scholar Klaeger, S. et al. The target landscape of clinical kinase drugs. Science 358, eaan4368 (2017). Hafner, M. et al. Multiomics profiling...
Spectrum and degree of CDK drug interactions predicts clinical performance. Mol. Cancer Ther. 15, 2273–2281 (2016). Article ADS PubMed Google Scholar Klaeger, S. et al. The target landscape of clinical kinase drugs. Science 358, eaan4368 (2017). Hafner, M. et al. Multiomics profiling...
Drug and food interactions Moderate abemaciclib food Applies to: abemaciclib Grapefruit juice can increase the blood levels of abemaciclib. This may increase side effects such as nausea, vomiting, diarrhea, abdominal pain, decreased appetite, mouth sores, blood clots, hair loss, liver pr...
[11]Kulanthaivel P,Mahadevan D,Turner PK,et al.Pharmacokinetic drug interactions between abemaciclib and CYP3A inducers and inhibitor[J].Cancer Res,2016,76(14S):CT153. [12]Patnaik A,Rosen LS,Tolaney SM,et al.Efficacy and safety of abemaciclib,an inhibitor of CDK4 and CDK6,for patients ...