还证明了外源性鞘内注射 rDKK3 可抑制 p-ASK1、p-JNK、p-p38 的表达,促进小胶质细胞从 M1 型向 M2 型转化,减少促炎细胞因子产生与 SNI+Vehicle 的大鼠相比。通过鞘内施用 Kremen-1 siRNA 或 DVL-1 siRNA,发现效果被逆转。最终证实DKK3通过抑制 ASK-1/JNK/p-38 介导的小胶质细胞极化和神经炎症来改善...
Mouse Alpha-Fetoprotein (AFP) Mouse mAb (A11865), validaed in WB,IHC-P,IF/ICC,ELISA and tested in Human. 100% Guaranteed. ABclonal provides trial size antibody samples for target detection. Replacement to Abcam, Santa Cruz, Sigma and CST antibody.
Rabbit SIRT6 Rabbit pAb (A18468), validaed in ELISA,WB,IHC-P and tested in Human,, Mouse,, Rat. 100% Guaranteed. ABclonal provides trial size antibody samples for target detection. Replacement to Abcam, Santa Cruz, Sigma and CST antibody.
Rabbit Phospho-eNOS-S1177 Rabbit pAb (AP0515), validaed in WB,IHC-P,ELISA and tested in Human,, Mouse. 100% Guaranteed. ABclonal provides free trial antibodies for target detection. Replacement to Abcam, Santa Cruz, Sigma and CST antibody.
Rabbit GFAP Rabbit pAb (A0237), validaed in WB,IHC-P,IF/ICC,ELISA and tested in Human,, Mouse,, Rat. 100% Guaranteed. ABclonal provides free trial antibodies for target detection. Replacement to Abcam, Santa Cruz, Sigma and CST antibody.
Rabbit CORIN Rabbit pAb (A10404), validaed in ELISA,WB and tested in Human,, Mouse,, Rat. 100% Guaranteed. ABclonal provides free trial antibodies for target detection. Replacement to Abcam, Santa Cruz, Sigma and CST antibody.
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Rabbit TDP-43/TARDBP Rabbit pAb (A17114), validaed in ELISA,WB,IHC-P,IF/ICC and tested in Human,, Mouse,, Rat. 100% Guaranteed. ABclonal provides trial size antibody samples for target detection. Replacement to Abcam, Santa Cruz, Sigma and CST antibody.
WBIHC-P ABflo® 488-conjugated Donkey anti-Rabbit IgG (H+L) AS035 IF/ICCFC ABflo® 488-conjugated Goat anti-Rabbit IgG (H+L) AS073 IF/ICCFC ABflo® 555-conjugated Goat anti-Rabbit IgG (H+L) AS058 IF/ICCFC ABflo® 405-conjugated Goat anti-Rabbit IgG (H+L) ...
Rabbit SIRT2 Rabbit pAb (A0273), validaed in ELISA,WB,IHC-P,IF/ICC and tested in Human,, Mouse,, Rat. 100% Guaranteed. ABclonal provides free trial antibodies for target detection. Replacement to Abcam, Santa Cruz, Sigma and CST antibody.