This protein also functions as a transporter in the blood-brain barrier.别名 ABC20,CD243,CLCS,GP170,MDR1,P-GP,PGY1 基因id Chromosome:7 Start: 87133175 End: 87342611 Strand: -1药物 卡铂 顺铂 紫杉醇 突变与药物 I1145I S893T S893A/T EXPRESSION ...
1.Atsushi Kodan et al. ABCB1/MDR1/P‐gp employs an ATP‐dependent twist‐and‐squeeze mechanism to export hydrophobic drugs. FEBS Letters, 2020, doi:10.1002/1873-3468.14018. 2.Protein twist and squeeze confers cancer drug resistance https://medicalxpress.com/news/2020-12-protein-confers-cancer...
ABCB1重组蛋白;高活性/Recombinant human ABCB1 protein 价格￥737 起批量≥1支 最小起订1支 供货总量999支 发货地址湖北省武汉市 建议售价￥899/支 更新日期2025年03月21日 产品规格10ug/50ug/100ug/1mg 即时洽谈立即询价查看联系方式 收藏产品发送留言 ...
这种蛋白也作为血脑屏障的转运蛋白发挥作用。 The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct su...
该ABCB1(P糖蛋白)产品的应用类型详情查看产品说明书。 免疫原 Human recombinant protein fragment corresponding to amino acids 995-1280 of human ABCB1 (NP_000918) produced in SF9 cell. 来源宿主 mouse 反应性 该Cdx1产品的反应性详情查看产品说明书。
Martinelli M, Carinci F, Morselli PG, Palmieri A, Girardi A, Farinella F, Baciliero U, Scapoli L. Study of ABCB1 multidrug resistance protein in a common orofacial malformation. Int J Immunopathol Pharmacol 2011; 24(2):1-5.Martinelli M, Carinci F, Morselli PG, Pa...
ABCB1 (also known as P-gp/ P-glycoprotein, MDR1/multidrug-resistance 1) is a plasma membrane protein first discovered in multidrug resistant tumor cells. ABCB1 can extrude a large number of medically relevant compounds from cells and causes drug resistance. ABCB1 is expressed in a variety of...
The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. [SEQUENCE ] [ ...
ZY061Hu012蛋白二硫键异构酶(PDI)重组蛋白Recombinant Protein Disulfide Isomerase (PDI)Homo sapiens (Human) ZY061Hu013血小板衍生生长因子受体β(PDGFRβ)重组蛋白Recombinant Platelet Derived Growth Factor Receptor Beta (PDGFRb)Homo sapiens (Human)
The expression of drug efflux pump ABCB1/P-glycoprotein (P-gp), a transmembrane protein belonging to the ATP-binding cassette superfamily, is a leading cause of multidrug resistance (MDR). We previously curated a dataset of structurally diverse and selective inhibitors of ABCB1 to develop a phar...