The endpoints include overall response rate (ORR), duration of response (DoR), disease control rate (DCR) and progression-free survival (PFS) per independent central review (ICR) as well as overall survival (OS). AbbVie previously announced positive topline results from the LU...
Advances in high-dose chemotherapy and stem cell transplantation have improved overall survival (OS) and event-free disease periods in MM (Lonial et al., 2012, J Clin Oncol 30:1953-1959), although relapses are inevitable. Newer therapeutic agents, such as proteasome inhibitors (currently ...
Diabetes Res Clin Pract 2000;47:199–207.Karlsson MG, Ludvigsson J 2000 The ABBOS-peptide from bovine serum albumin causes an IFN-␥ and IL-4 mRNA response in lymphocytes from children with recent onset of type 1 diabetes. Diabetes Res Clin Pract 47:199-207...
ABB-REM615_产品说明 热度: Databaseabbreviationlist General SHAGAPLATE2016/09/28 ShortformName AbdAccumulatorblowdown Aboabort Absabsolute Accacceleration Ackacknowledge Acptaccepted Actactual Activactive Adjadjust(ment) AdvAdvance AfcAutomaticflatnesscontrol ...
ECHO 研究更新,阿可替尼联合 BR 可实现一线 MCL PFS 和 OS 双重获益 在2025 最新版 NCCN 指南中,阿可替尼联合 BR 方案较 2005 年版第一本的唯一更新点,其重要性不言而喻。阿可替尼联合苯达莫司汀和利妥昔单抗的 ABR 方案被推荐主要是基于 Ⅲ期 ECHO...
Abb plc说明 DatabaseabbreviationlistGeneral ShortformAbdAboAbsAccAckAcptActActivAdjAdvAfcAgcAiBdAIAlgAllAnAoBdApcAppAprArAsgatAuAutoAuxAvBadjBalBasBatBdgBdgMagBeaBedsBeosBfzBhdBindBkBknfBlBldBlkBlOffBlsBmBn NameAccumulatorblowdownabortabsoluteaccelerationacknowledgeacceptedactualactiveadjust(ment)AdvanceAutomatic...
图5. DL02研究的OS数据 DESTINY-Lung02亚组分析(5.4mg/kg)显示,不论既往是否接受过免疫治疗、不论有无脑转移,ORR均优异,既往接受、未接受抗PD-(L)1治疗患者的ORR分别为49.3%和51.9%,有和无中枢神经系统(CNS)转移患者的ORR分别为60....
背景:在接受铂类化疗和PD-1/L1抑制剂治疗后出现进展的转移性尿路上皮癌(mUC)患者中,戈沙妥珠单抗(SG)显示出良好的抗肿瘤活性——客观缓解率(ORR)为27%,中位总生存期(OS)为10.5个月。在接受以铂类为基础的化疗后,SG和帕博利珠单抗联合治疗是安全有效的。纳武利尤单抗(NIVO)1mg/kg +伊匹单抗(IPI)3mg/kg...
该结果与全球患者的研究结果一致,后者显示,与安慰剂相比,度伐利尤单抗可将死亡风险降低27%(OS [HR]0.73;95% CI 0.57-0.93;p=0.0104),将疾病进展或死亡风险降低24%(PFS [HR]0.76;95% CI 0.61-0.95;p=0.0161)。 阿斯利康中国肿瘤业务总经理关冬梅表示: "很高兴看到中国专家和患者持续为全球临床试验做出重要贡...
- 《J Clin Psychiatry》 被引量: 178发表: 1987年 Treatment of compulsive sexual behaviour with naltrexone and serotonin reuptake inhibitors: two case studies. alcoholism, borderline personality disorder with self-injurious behaviour, cocaine abuse, mental retardation with self-injurious behaviour and ...