Which types of cells lack(s) a nucleus? What is the difference between a normal cell and a cancer cell? What are the different types of cell divisions? What are the characteristics of each? What is a typical cell size for bacteria? For eukaryotes?
Mucin has a key role both in normal tissue histology and in cancer47, including in the appendix. Primarily expressed by epithelial cells on apical surfaces, secreted mucins form a physical barrier that protects epithelia from adverse conditions and limits exposure to commensal bacteria. However, the...
Skin cancer is a common problem in Australia and indeed around the world. Within the domain of e-Health, there appears to be no satisfactory clinical software that follows the flow of a normal skin cancer examination. This paper introduces a system that was specifically designed, coded and ...
However, although the intracellular H2O2 level in most cancer cells is higher than that in normal cells, the endogenous H2O2 is still not nearly enough to meet the demand for satisfactory chemodynamic efficacy10,19,20,21,22. As far as this is concerned, the introduction of H2O2 self-supplying...
Because a cell cycle checkpoint deficiency is also crucial for tumorigenesis and is a typical characteristic of cancer cells, although not a transient property, we performed cancer mutational signature analysis of our stem cells. This assay was developed to analyze the huge body of cancer sequence ...
A typical droplet of blood contains 50 microliters. Xu and his colleagues tested their lab-on-a-chip by equipping one of its channels to look for MMP14, an enzyme released by tumors that has been linked to cancer progression. The enzyme attacks healthy cells in ways that seem t...
The concept of a specialized population of cells within tumors termed CICs, or alternatively cancer stem cells or tumor-initiating cells, has received considerable recent interest. CICs represent a subpopulation of transformed cells, distinct from more “differentiated” tumor cells, and are thought to...
METTL14 R298P mutation is identified mainly in patients with endometrial cancer,29 and we showed that this mutation appears to be heterozygous in these patients (Figure 2D). As previously reported,16 we observed that cell proliferation is promoted in endometrial cancer cells harboring the heterozygous...
While BRCA1+ induces breast cancer by causing genome instability, most of the knowledge is known about somatic genome instability in breast cancer cells but not germline genome instability. Methods Using the exome-sequencing method, we analyzed the genomes of blood cells in a typical BRCA1+ ...
Why do virtually all cancer cells converge on a common DNA methylation pattern and how does this pattern affect development and progression of disease? What is the function and disease relevance of the intermediate CGI hypermethylation and genome-wide hypomethylation typical of cancer (and aging)? Wh...