Tissue engineering is a rapidly growing field in biotechnology. The use and packaging of synthetic materials, biologic compounds, and cellular components of specific tissues can be envisioned to replace physiologic function of diseased organs. Long-term ex vivo therapy for kidney failure has been ...
Malignant peripheral nerve sheath tumors (MPNSTs) are very rare soft-tissue tumors. These tumors originate from Schwann cells or pluripotent perineural cells of the neural crest. An isolated MPNST of the kidney is extremely rare and has been reported in only six cases to date. A 30-year-old...
Our approach here was to modify this vector system by exchanging the constitutive promoter with tissue- or tumor-specific ones to generate a vector, which will episomally express the transgene in the target cell type only, but being lost in all other cell types. Recently, similar effects with...
Malignant rhabdoid tumor of kidney (MRTK) is an uncommon and aggressive malignancy, primarily affecting infants and young children [1]. Its occurrence in adults is exceedingly rare, making diagnosis and management challenging. Here, we present a case of MRTK in an adult woman with a family histo...
The tumor has been reported to enlarge during pregnancy and shrink after delivery, suggesting a possible hormonal dependence [7]. In men, such tumors may originate from any part of the urinary tract, including the kidney, which is reported to be the most common site. Other sites of origin ...
Antianemic Agent; Chronic Kidney Failure; Continuous Erythropoiesis Receptor Activator 抗贫血剂;慢性肾功能衰竭;持续型红细胞生成素受体激活剂 经典高被引论文: Prevalence of chronic kidney disease in China: A cross-sectional survey 中国慢性肾脏病患病率的横断面调查 ...
The concept of intratumoural microbiota was subsequently proposed. Microbiota could colonise tumour tissues through mucosal destruction, adjacent tissue migration, and hematogenic invasion and affect the biological behaviour of tumours as an important part of the tumour microenvironment. Mechanistic studies ...
However it also has limited utility in vivo due to streptavidin's high affinity to fibronectin and kidney tissue [22,23]. In recent years, neutravidin is emerging as an alternative to avidin or streptavidin in avidin/biotin system-based pretargeting platforms [24]. Neutravidin is a de...
of cells within the myocardial tissue5. These developmental abilities also translate into a regenerative role. Adult zebrafish hearts are capable of regeneration, and developmental epicardial genes become highly expressed at the infarcted region, coinciding with the restoration of cardiac muscle6,7. ...
Rates of metastasis to the kidney are particularly low, ranging from 2.8–3.8% for papillary and 6–20% for follicular variants of well-differentiated thyroid cancers (WDTCs). In rare instances, tumor-to-tumor metastasis between two true primary neoplasms can occurs. This medical phenomenon has ...