Two papers in this issue of Oncogene (Cheli et al., 2011; Strub et al., 2011) reveal that low-Mitf cells can initiate tumors with high efficiency, and that Mitf blocks senescence by regulating genes implicated in S-phase progression and mitosis....
6k). Similar to a typical vertebrate neuroepithelium, in the embryoids, mitosis occurred at or near the apical surface (Fig. 6l) while cell bodies of neurons expressing class III β-tubulin (TUBB3) were located basally (Fig. 6m). At D8, TUBB3 expressing neurons extended their axons ...
Geoghegan I, Steinberg G, Gurr S (2017) The role of the fungal cell wall in the infection of plants. Trends Microbiol 25(12):957–967. https://doi.org/10.1016/j.tim.2017.05.015 Article CAS PubMed Google Scholar Gladfelter AS (2006) Nuclear anarchy: asynchronous mitosis in multinucleate...
Internodal cells of the main axis develop from a uninucleate segment cell (Pickett-Heaps, 1967). This nucleus and all further nuclei divide in the absence of a spindle, a process that is referred to as amitosis (equal division) or fragmentation (unequal division) (Bucher, 1959; Kisser, 192...
This Golgi arrangement is dynamic, under- going regulated disassembly/reassembly during mitosis, directed migration and polarized secretion [6]. The rib- bon also disassembles in response to membrane depo- larization, raised intracellular calcium, viral infection, autophagy induction and genotoxic ...
While DNA and RNA methods are routine to disrupt the expression of specific genes, complete understanding of developmental processes requires also protein methods, because: oocytes and early embryos accumulate proteins and these are not directly affected by DNA and RNA methods. When proteins in the ...
The next three examples show nuclear stains using antibodies to cell cycle related proteins. The first (Figure 6.14A) shows the distribution of cyclin A through the cell cycle. The cyclin is degraded during mitosis. In the second (Figure 6.14B) the cells were stained for an antibody to p-...
Which phase of mitosis (prophase, metaphase, anaphase, or telophase) does a dividing cell spend most of its time in?Mitosis:Walther Flemming called the cell division pattern first observed in many cells across kingdoms as mitosis in 1882. Other alternative...
GSEA revealed a broad picture of increased cell prolif- eration and reduced differentiation associated with net- work hits in mice and low network metagene activity in human tumours (the concordant gene expression pattern), as demonstrated by significant enrichment of multiple genesets (see ...
Whereas, in untreated samples, cytoplasmic microtubules faded when the cells underwent mitosis and reassembled again when the cells conclude cell cycle, which is usual. There were two propositions recommended for the steady vanishing of MTs treated with spongistatins: 1) simply after fragmentation ...