The advantage of this technique is that a spatial resolution neither of the star nor of the planet is required. The difficulty is rather that the projected size of the planet in front of the star is very small; in the case of the Earth in front of the Sun, seen from another planetary...
Single-cell resolution with high-throughput cell identification, cell separation, and efficient cell transformation are among the new developments. Strain selection and development, cell cultivation, and downstream processing are all topics of research [65]. The conditions for a microfluidic device for ...
The COMET assay measures DNA strand breaks at the individual cell level, and it can be applied both in sperm (as described above) and peripheral blood cells. The fluorescence is calculated to measure the level of DNA damage [106]. The COMET assay is the only test that makes it possible ...
On the basis of these analyses, we formulated the following hypothesis. McSCs may differentiate into an intermediate differentiation (TA-like) state at the whole population level in the growing HG following cues of regenerative stimuli, and McSC maintenance may rely on their dedifferentiation. To te...
we verified the MAG reconstruction based on sequencing coverage at the whole genome level. To alleviate scaffold size-induced unevenness, the coverage used here was calculated by using a fixed window of 500 bp with 250 bp overlap, while the above analyses (Figs.1and2) were based on the avera...
SPO2. Data shown as mean ± s.e.m.,n = 6 independent wells. Data were analyzed with one-way ANOVA followed by Tukey’s multiple comparisons test.F(6,35) = 10.18. Spearmanrcorrelation between RSPO2 level in medium and adipocyte ratio (jright). NS, not significant.l–n,...
Optimal repair of muscle is associated with initial construction of an ECM scaffold, followed by feedback mechanisms to ensure the resolution of fibrosis [111]. When feedback mechanisms are compromised or when injury is repetitive, excess collagen deposition by fibroblasts results in scar tissue forma...
While it is common to restrict IE systems to only take into account named bioentities as objects participating in relationships, consideration of extended named entities allows a better resolution of the actual statements in the sentence. Consider the following example: ...
They found that response rates were higher when less stringent fever resolution definitions were used, especially in low-risk patients. The modified definitions of fever resolution were: no fever for 24 hours before the resolution of neutropenia; no fever at the 7-day post-therapy follow-up ...
single-base detection at a genome-wide level [6,7]. SMRT sequencing can detect 5mC modifications based on polymerase kinetics at 250× coverage [8]. However, this detection is not the result of direct 5mC detection at single-molecule resolution but rather the aggregation of the subtle impact...