YTH Domain: A Family of N(6)-methyladenosine (m(6)A) Readers. Genomics Proteomics Bioinform. 2018, 16, 99-107. [CrossRef] [PubMed]Liao S, Sun H, Xu C. YTH domain: a family of N(6)-meth- yladenosine (m(6)A) readers. Genom Proteom Bioinform. 2018;16:99-107....
N6-methyladenosine (m6A) modification has been convincingly identified to be a critical regulator in human cancer. However, the contribution of m6A to NSCLC gefitinib resistance is still largely unknown. Here, we screened and identified that m6A methyltr
Recent years have seen substantial progress in m6A epitransc... K Taketo,M Konno,A Asai,... - 《International Journal of Oncology》 被引量: 9发表: 2018年 YTH Domain: A Family of N6-methyladenosine (m6A) Readers. Like protein and DNA, different types of RNA molecules undergo various ...
RNA N6-methyladenosine (m6A) is the most abundant RNA modification in the human and a key determinant in posttranscriptional regulation of messenger RNA (mRNA) splicing, translation, and degradation.1,2 Emerging studies have unveiled a critical role of RNA m6A modification by RNA modification enzyme...
N6-methyladenosine (m6A) and its reader proteins YTHDC1, YTHDC2, and YTHDF2 have been shown to exert essential functions during spermatogenesis. However, much remains unknown about m6A regulation mechanisms and the functions of specific readers during th
N6-methyladenosine (m6A), conferred by its active writer, METTL3, to regulate cell state transitions through alterations in the transcriptional profile of these cells. Our objective was to determine if m6A-modification deposition via METTL3 is a regulator of MuSC/myoblast state transitions in vitro...
艾德科技-尿液样本 m6A 定量检测试剂盒(比色法)(A-P-9015)-MethylFlash Urine N6-methyladenosine (m6A) Quantification Kit (Colorimetric)/艾德科技-尿液样本 m6A 定量检测试剂盒(比色法)(A-P-9015)-MethylFlash Urine N6-methyladenosine (m6A) Quantification K
To date, more than 150 types of modifications have been reported. Among them, N6-methyladenosines (m6A), 5-methylcytosines (m5C) and N1-methyladenosines (m1A), pseudouridine (Ψ) modifications and 2′-O-methylations (2′-O-Me) have been found to be the prevalent ones [1,2]. m6A ...
Mechanistically, the upregulated level of TRAF1 in sunitinib-resistant cells was derived from increased TRAF1 RNA stability, which was caused by an increased level of N6-methyladenosine (m6A) in a METTL14-dependent manner. Moreover, in vivo adeno-associated virus 9 (AAV9) -mediated transduction...
N6-methyladenosine (m6A) modification is the most abundant type of RNA modification which is mediated by three distinct classes of proteins called m6A writers, readers, and erasers. Accumulating evidence has been made in understanding the role of m6A modification of non-coding RNAs (ncRNAs) in ...