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By analysis of outlier loci and allele frequency change over time we traced back the 2NS/2AS translocation of Aegilops ventricosa to one cultivar, “Cardos” (registered in 1998) which was the first among the panel to contain this translocation. A “selective sweep” for this important ...
For each of the 44,817 SNPs, we constructed a test (see Methods) to determine whether the observed change in allele frequency could be explained by drift or alternatively must be due to selection. From this analysis, we found that the observed allele frequency changes exceeded the likely ...
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waddR - R package for testind distributional differences, using 2-Wasserstein distance, decomposed into change in location, shape, size, proportion of zeros (CMH test). Methods for one/multiple replicates per condition. Compared with scDD, SigEMD. Fast. In real data, detects similar genes to ...
Change in local frustration index: https://github.com/gersteinlab/frustration TFImpute: multi-task learning from ChIP-seq data across factors and tissues to impute TF binding for an unassayed tissue/factor combination: https://bitbucket.org/feeldead/tfimpute PPI https://www.ncbi.nlm.nih.gov/...
(a) Abundance of lymphocyte subsets in peripheral blood of CID patients analysed for TCRαβ repertoire diversity. Reference are values taken from[62]. Vβ-usage analysed by flow cytometry for CD8+ (b) and CD4+ (c) T cells. Data are depicted as fold change over mean reference values. Gr...
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Provided the frequency of data collection is sufficient, LTRS/LDVS makes it possible to assess individual changes in performance more sensitively than conventional paper–pencil assessments, and without the inconvenience of having to compare with change in a normative sample subject to interindividual ...