Bacterial toxins represent a vast reservoir of biochemical diversity that can be repurposed for biomedical applications. Such proteins include a group of predicted interbacterial toxins of the deaminase superfamily, members of which have found applicatio
参考文献 1. Mok, B. Y., et al. A bacterial cytidine deaminase toxin enables CRISPR-free mitochondrial base editing.Nature583, 631–637 (2020). 2. Mok, B.Y., et al. CRISPR-free base editors with enhanced activity and expanded targeting scope in mitochondrial and nuclear DNA.Nat Biotechnol...
1. Mok, B. Y., et al. A bacterial cytidine deaminase toxin enables CRISPR-free mitochondrial base editing.Nature583, 631–637 (2020). 2. Mok, B.Y., et al. CRISPR-free base editors with enhanced activity and expanded targeting scope in mitochondrial and nuclear DNA.Nat Biotechnol(2022)....
1. Mok, B. Y., et al. A bacterial cytidine deaminase toxin enables CRISPR-free mitochondrial base editing.Nature583, 631–637 (2020). 2. Mok, B.Y., et al. CRISPR-free base editors with enhanced activity and ...
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et al. A bacterial cytidine deaminase toxin enables CRISPR-free mitochondrial base editing. Nature 583, 631–637 (2020). Article CAS PubMed PubMed Central Google Scholar Sarwar, Z. et al. GcsR, a TyrR-like enhancer-binding protein, regulates expression of the glycine cleavage system in ...
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A bacterial cytidine deaminase toxin enables CRISPR-free mitochondrial base editing Nature, 583 (2020), pp. 631-637, 10.1038/s41586-020-2477-4 View in ScopusGoogle Scholar 122 Y. Yang, H. Wu, X. Kang, Y. Liang, T. Lan, T. Li, T. Tan, J. Peng, Q. Zhang, G. An, et al. ...
et al. A bacterial cytidine deaminase toxin enables CRISPR-free mitochondrial base editing. Nature 583, 631–637 (2020). Article CAS PubMed PubMed Central Google Scholar Mok, B. Y. et al. CRISPR-free base editors with enhanced activity and expanded targeting scope in mitochondrial and ...
Mok, B. Y. et al. A bacterial cytidine deaminase toxin enables CRISPR-free mitochondrial base editing.Nature583 Article Komor, A. C., Kim, Y. B., Packer, M. S., Zuris, J. A. & Liu, D. R. Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage...