1. Formation of glycosidic bonds These are the bonds which join single sugars (monosaccharides) together to form double sugars (disaccharides) and multiple sugars (polysaccharides). 比如在maltose的合成过程中,涉及到两个α-glucose的condensation形成1,4 alpha-glycosidic bond。 而在cellulose的合成过程中,涉...
(1.38 Å) for PPA. Acarbose was modified to represent a five-residue glucose oligomer, linked by α1–4 glycosidic bonds. Crystallographic waters were retained, except for those clashing with atoms of the modified substrate. The AHA and PPA systems were prepared for EVB/MD simulations33,...
β-CDs are cyclic oligosaccharides consisting of seven D-glucose units linked by α-1,4 glycosidic bonds forming a ring-like structure. While the exterior of the structure is hydrophilic, the centre, with a diameter of approximately 5–8 Å, is hydrophobic and allows fewer polar components ...
years that the enzyme involved in debranching of a phosphorylase limit dextrin has two different activities-a transferase activity, transferring maltotriosyl or maltosyl units, thereby exposing the a-1,6 linkage, and a hydrolytic activity, acting on the glycosidic bond at the branch point (4). ...
existence of alpha-amylase (HXA) encoded by alpha-amylase gene AMY2B in healthy humans was examined using a fluorogenic substrate, FG5P (FG-G-G-G-G-P: FG, 6-deoxy-6-[(2-pyridyl)amino]-D-glucose residue; G, glucose residue; P, p-nitrophenyl residue; -, alpha-1,4-glycosidic bond...
Re: synthesis of a glycosidic bond «Reply #24 on:January 13, 2022, 06:58:55 PM » Our first glycosylation attempts will use the Schmidt glycosyl donor, a trichloroacetimidate. The choice of base strongly influences the configuration of the trichloroacetimidate. One thing that I am not yet...
non-covalent interactions; density functional theory; methylated cyclodextrins; dimethyl-β-cyclodextrin; hydrogen bond Graphical Abstract1. Introduction Cyclodextrins (CDs) consist of circularly connected glucose units, joined by α-1,4 glycosidic bonds (Figure 1a), and are well-known to encapsulate ...
PGase is the main heterogeneous pectinase catalyzing the hydrolysis of the pectin polymer into galacturonic acid by cleaving the α-1,4-glycosidic bond [32,55]. Starch is the main component of maize grains, which is decomposed by amylase, a starch-degrading enzyme. The lytic behavior of this...
capsici[3, 4]. PELs are enzymes which specifically catalyze the cleavage of the α-1,4-glycosidic linkages in the unesterified polygalacturonic acid (PGA) regions of plant cell walls and produce an unsaturated bond between C4 and C5 of each d-galacturonic acid unit [5, 6], resulting in ...
Density functional theory was used to study the glycosidic bond cleavage in deoxynucleotides with the main goal to determine the effects of the nucleobase, hydrogen bonding with the nucleobase, and the (bulk) environment on the reaction energetics. Since direct glycosidic bond cleavage is a high-...