The aim of this study was to quantify the tumor uptake of [68Ga] Gallium-FAP-2286 within primary solid tumors, adjacent excised tissues, and metastatic lesions. Methods In this prospective study, 21 patients (average age 51.9) with various diagnoses of remaining and metastatic cancers ...
The PET/CT scans displayed substantial absorption of [68Ga]Ga-FAP-2286 in tumor lesions in all patients (100% (21/21)). Irrespective of the tumors' origins (epithelial or mesothelium) and whether they exhibited local recurrence, distant recurrence, or metastatic lesions, the PET/CT scans ...
在安全性上,与传统治疗相比,68Ga/177Lu-FAP-2286 因精准的靶向机制,大幅减少了对正常组织的不良影响,副作用明显降低,极大地提升了患者的生活质量,且不会累及其他器官或系统,全身安全性良好。 治疗前,患者需化验血常规、生化及评估PET/CT等,医生能够依据每位患者的具体病情、身体状况等因素,量身定制适宜的治疗方案,...
The aim of this study was to quantify the tumor uptake of [Ga-68] Gallium-FAP-2286 within primary solid tumors, adjacent excised tissues, and metastatic lesions. Methods: In this prospective study, 21 patients (average age 51.9) with various diagnoses of remaining and metastatic cancers ...
Fibroblast activation protein (FAP), expressed in the tumor microenvironment of a variety of cancers, has become a target of novel PET tracers. The purpose of this report is to evaluate the imaging characteristics of Ga-68-FAP-2286, present the first-to our knowledge-dosimetry analysis to date...