TheD-altro phosphonate analog,2, of 5-deoxy-5-methylthioribose 1-α-phosphate,1, was prepred in four steps from the known synthetic intermediate,3. The analog does not apparently inhibit regeneration of methionine, in competition with the natural metabolite1.Figure optionsView in workspace...
The phylogenetic analysis of protein sequences belonging to IF2B-like family along with PH0702 and PH0208 revealed that PH0702 belonged to methylthioribose-1-phosphate isomerase (MTNA) group of proteins, whereas, PH0208 was found to be clustered in the group of ribose-1,5-bisphosphate ...
In silico analysis suggests that PH0702 and PH0208 encode for methylthioribose-1-phosphate isomerase and ribose-1,5-bisphosphate isomerase, respectively, rather than aIF2Bβ and aIF2Bδdoi:10.1016/j.gene.2015.08.048Prerana GogoiAmbuj Srivastava...