5-lipoxygenase inhibitor具有抑制5-脂肪氧合酶作用的式I新化合物及其可药用盐,其中Ar The novel compounds I and their pharmaceutically acceptable salts have 5-lipoxygenase inhibitory action of the formula, wherein Ar罗德尼·W·史蒂文斯真野高司中尾一成奥村祥征...
[1] Hyun-Jeong Kwak, et al. The cardioprotective effects of zileuton, a 5-lipoxygenase inhibitor, are mediated by COX-2 via activation of PKCδ. Cellular Signalling 22 (2010) 80-87. [2] Tu XK, et al. Zileuton reduces inflammatory reaction and brain damage following permanent cerebral ische...
This invention relates to novel AKBA analogs of the formula I given below: Where in R1, R2, R3, R4 and R5 in each of the said analogs are: 1. R1═OCHO, R2═H, R3═COOH, R4 & R5═O 2. R1═OCOCH2Cl, R2═H, R3═COOH, R4 & R5═O 3. R1═5′-O-methylgalloyloxy
Zileuton是一种有效的,选择性的5-lipoxygenase抑制剂,具有抗炎的作用。注:本品仅可用于科研实验,严禁用于临床医疗及其他用途!CAS号:111406-87-2别名:A 64077;Abbott 64077纯度:99.84%分子式:C11H12N2O2S分子量:236.29结构式:储存条件:-20℃,有效期2年,溶入溶剂后-20℃请尽量在一个月内使用。相关搜索:5-...
5-LOx-in-2 is a 5-lipoxygenase inhibitor (5-LOX) with an IC50 value of 0.33 μM. 5-lox-in-2 inhibits 5-LOX action IN a dose-dependent manner. 5-LOX-IN-2 can reduce the cell activity of kidney cancer cells and induce apoptosis, and can be used in cancer research. 靶点活性 5-...
The redox-type inhibitor nordihydroguaiaretic acid (NDGA) is lodged in the 5-LOX active site, now fully exposed by disordering of the helix that caps it in the apo-enzyme. In contrast, the allosteric inhibitor 3-acetyl-11-keto-beta-boswellic acid (AKBA) from frankincense wedges between ...
PC-3 cells are an appropriate model for studying the mechanism responsible for 5-lipoxygenase inhibitor-induced cellular suicide. Prostate 37:161–173, 1998. © 1998 Wiley-Liss, Inc. 展开 关键词: PC-3 cells 5-lipoxygenase inhibitors programmed cell death ...
Keeping asparagus fresh with lipoxygenase inhibitor; 脂氧合酶抑制剂用于芦笋保鲜的研究 更多例句>> 补充资料:羟氧酶 分子式:CAS号:性质:又称加单氧酶,羟化酶,羟氧酶。一类催化有机物分子直接加氧的酶。它催化一个氧原子参人底物,另一个氧原子被还原成水。酶反应需要还原型辅因子,如FAD、NADP、抗坏血酸...
产品描述 5-LOX-IN-1 is a 5-Lipoxygenase (5-LOX) inhibitor (IC50: 2.3 μM).5-LOX-IN-1 can be used for cancer research. 靶点活性 5-LOX:2.3 μM 体外活性 5-LOX-IN-1 (0-10 μM) 对5-脂氧合酶(5-LOX)活性表现出抑制作用,其IC50值为2.3 μM。[1] 化学信息 分子量 350.43 分子式 ...
5-Lipoxygenase Inhibitor, MK591 会员价请登录市场价￥1895 原厂型号5.32606.0001 贝雷猫货号RH156086 品牌默克密理博/Millipore 单件重量1kg 货期45天 单位:盒包装:盒库存:0 数量:盒+-1盒起订,增量1盒 累计成交0笔0条评价 选择其它规格 商品名 贝雷猫货号 ...